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von WILLEBRAND FACTOR prevents and treats bleeding episodes in people with von Willebrand disease (vWD), a condition caused by low levels of clotting protein. It works by increasing these protein levels in your body. This helps your blood clot normally, which reduces bleeding. Compare coagulation factors.

Prescription Settings

Specialty Drug: Specialty drugs are often expensive and may need to be filled through specialty pharmacies. Learn More

What is Vonvendi?

What should I tell my doctor?

They need to know if you have any of these conditions:

Have been told you have inhibitors to von Willebrand factor or blood factor VIII
An unusual or allergic reaction to von Willebrand factor, factor VIII, mice, hamsters, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Breastfeeding

How should I use this drug?

This medication is injected into a vein. It is usually given by your care team in a hospital or clinic setting. It may also be given at home.

If you get this medication at home, you will be taught how to prepare and give it. Use exactly as directed. Take it as directed on the prescription label. Keep taking it unless your care team tells you to stop.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

This medication comes with INSTRUCTIONS FOR USE. Ask your pharmacist for directions on how to use this medication. Read the information carefully. Talk to your pharmacist or care team if you have questions.

Talk to your care team about the use of this medication in children. Special care may be needed.

What if I miss a dose?

If you get this medication at the hospital or clinic: It is important not to miss your dose. Call your care team if you are unable to keep an appointment.

If you give yourself this medication at home: If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. Call your care team with questions.

Where should I store this drug?

Keep out of the reach of children and pets.

Store in a refrigerator or at room temperature at or below 30 degrees C (86 degrees F). Do not freeze. Keep this medication in the original packaging until you are ready to take it. Protect from light. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
If you cannot return the medication, ask your pharmacist or care team how to get rid of this medication safely.