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Trihexyphenidyl

Trihexyphenidyl Side Effects

Hope Chang, PharmD, AAHIVPKristianne Hannemann, PharmD
Reviewed by Hope Chang, PharmD, AAHIVP, Kristianne Hannemann, PharmD
Last reviewed on December 21, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dry mouth
  • Blurry vision
  • Dizziness
  • Nausea
  • Nervousness

Less Common Side Effects

  • Gut blockage
  • Hallucination (seeing things that aren't there)
  • Erratic behavior
  • Memory problems
  • Constipation
  • Headache

Trihexyphenidyl serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Neuroleptic malignant syndrome: stiff muscles, sweating, fever, fast heartbeat, irregular pulse

Source: DailyMed

The following Trihexyphenidyl side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Fever that does not go away, decreased sweating
  • Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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