Skip to main content
Glycopyrrolate

Glycopyrrolate Side Effects

Shifali Patel, PharmDDaisy Chau, PharmD
Reviewed by Shifali Patel, PharmD, Daisy Chau, PharmD
Last reviewed on February 6, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dry mouth
  • Less sweating
  • Difficulty urinating
  • Constipation
  • Nausea
  • Vomiting
  • Feeling bloated

Less Common Side Effects

  • Vision changes or blurred vision
  • Higher heart rate
  • Loss of taste
  • Headache
  • Dizziness
  • Confusion
  • Nervousness
  • Sleepiness
  • Problems sleeping (insomnia)
  • Unable to get an erection (impotence)
  • Less breast milk production

Glycopyrrolate serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Worsening glaucoma: dilated pupils with eye pain or redness
  • Toxic megacolon: stomach pain, stomach swelling or bloating, fever, bloody diarrhea, fast heartbeat, confusion

Source: DailyMed

The following Glycopyrrolate side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain

chills

constipation

cough

decrease in the frequency of urination

decrease in urine volume

difficulty in passing urine (dribbling)

difficulty with breathing

ear congestion

feeling of warmth

fever

headache

loss of voice

nasal congestion

painful urination

redness of the face, neck, arms, and occasionally, upper chest

runny nose

sneezing

sore throat

unusual tiredness or weakness

Less common

Abdominal or stomach discomfort or pain

abdominal or stomach distension

chest pain

confusion

convulsions

dizziness

dry heaves

dry mouth

fainting

increase in heart rate

lightheadedness

pain or tenderness around the eyes and cheekbones

rapid breathing

shortness of breath or troubled breathing

stuffy nose

sunken eyes

thirst

tightness in the chest

vomiting

wheezing

wrinkled skin

Get emergency help immediately if any of the following symptoms of overdose occur:

low blood pressure

muscle weakness

trouble breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Altered mood

anxiety

attack, assault, or force

bloated

change in taste

chapped lips

crying

dry skin

dry tongue

excess air or gas in the stomach or intestines

full feeling

hyperventilation

irregular heartbeats

irritability

loss of taste

moaning

nervousness

pain

paleness of the skin

passing gas

rash

restlessness

shaking

trouble with sleeping

uncontrolled eye movements

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

why trust our exports reliability shield

Why trust our experts?

Shifali Patel, PharmD, worked as a pharmacist in a hospital setting for 3 years prior to joining GoodRx. As a hospital pharmacist, she reviewed medication orders for safety and accuracy, optimized medication therapy, provided clinical information to healthcare providers, and educated people about their medications.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

Was this page helpful?