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Trientine

Trientine Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on March 25, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low iron levels (iron deficiency)

Less Common Side Effects

  • Joint pain
  • Muscle spasm

Trientine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Myasthenia gravis: periods of muscle weakness, eyelid drooping, changes in vision or speech, difficulty swallowing
  • Systemic lupus erythematosus (SLE): on-and-off fever, tiredness, skin rash across cheeks and nose (butterfly rash), joint pain

Source: DailyMed

The following Trientine side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Lupus-like syndrome—joint pain, swelling, or stiffness, butterfly-shaped rash on the face, rashes that get worse in the sun, fever, unusual weakness or fatigue

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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