The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Diarrhea (12-47%)
- Stomach pain (21-28%)
- Nausea (11-26%)
- Vomiting (10-21%)
- Higher protein levels in urine (19%)
- Higher creatinine levels in blood (7-14%)
- Skin rash (8-13%)
These are common side effects for people who need blood transfusions. The three most common side effects for people with NTDT are nausea, rash and diarrhea.
Less Common Side Effects
- Sleep problems
- Dizziness
- Anxiety
- Change in skin color
- Blurry vision or other changes in vision
- Hearing loss
- Throat pain
Deferasirox serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Sudden kidney injury: feeling sick or weak, dehydration, urinating less than usual, confusion, blood in urine, swelling in the legs, ankles, or feet
- Liver damage: feeling tired or weak, poor appetite, losing weight without trying, dark urine, eyes and skin turning more yellow, upper right stomach pain
- Stomach bleeding: stomach pain, black and tarry stools, blood in the urine
- Low blood cell counts: frequent fevers or infections, bruise or bleed more easily, nose bleeds that don't stop
- Severe skin reactions: rash, skin pain or peeling, blisters, fever, sore throat, fatigue, facial swelling, swollen lips
Source: DailyMed
The following Deferasirox side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Black, tarry stools
bleeding gums
blood in the urine or stools
dark urine
decrease in the amount of urine
general feeling of tiredness or weakness
hives, welts, skin rash
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
light-colored stools
lower back or side pain
pale skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness, soreness, itching of the skin
sores, blisters
stomach pain, continuing
unusual bleeding or bruising
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
vomiting of blood or material that looks like coffee grounds
yellow eyes or skin
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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