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Deferoxamine

Deferoxamine Side Effects

Sarah Lobello Pearson, PharmDAllison Gourley, PharmD
Reviewed by Sarah Lobello Pearson, PharmD, Allison Gourley, PharmD
Last reviewed on April 18, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Irritation, pain, itching, or swelling at the site of injection
  • Headache
  • Nausea
  • Joint and muscle pain
  • Fever
  • Nausea
  • Vomiting
  • Stomach pain

Less Common Side Effects

  • Diarrhea
  • Asthma or trouble breathing
  • Rash
  • Muscle spasms
  • Hearing and vision problems
  • Slowed growth and bone changes

Deferoxamine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious fungal infections: fever, cough, chest pain, trouble breathing, headache, nausea, vomiting, stomach pain, blood in the stool
  • Serious allergic or infusion reactions: rash, hives, trouble breathing, flushing, dizziness, feeling confused, feeling cold, fast heart rate, chills
  • Serious lung problems: trouble breathing, pain while breathing, fast breathing, fast heart beat, finger tips or lips turning blue
  • Serious kidney problems: swelling in your feet or ankles, difficulty making urine, feeling tired, feeling confused, nausea, and difficulty breathing.

Source: DailyMed

The following Deferoxamine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Bluish fingernails, lips, or skin

blurred vision or other problems with vision

convulsions (seizures)

difficulty with breathing or fast breathing

fast heartbeat

hearing problems

redness or flushing of the skin

Less common

Diarrhea

difficult urination

fever

leg cramps

nausea

stomach and muscle cramps

stomach discomfort

unusual bleeding or bruising

vomiting

Incidence not known

Agitation

coma

confusion

cough

decreased urine output

depression

difficulty with swallowing

dizziness

headache

hives

hostility

irritability

itching

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

lethargy

muscle twitching

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid weight gain

shortness of breath

skin rash

stupor

swelling of the face, ankles, or hands

tightness in the chest

unusual tiredness or weakness

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Sarah Pearson is a practicing pharmacist with over 10 years of experience in the field. She received her doctorate in pharmacy from the University of Georgia in Athens, GA.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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