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Toremifene Coupon - Toremifene 60mg tablet

toremifene

Generic Fareston
Used for Breast Cancer
Used for Breast Cancer

Toremifene (Fareston) is a type of hormone therapy used to treat hormone-receptor positive (HR+) metastatic breast cancer in postmenopausal females. It’s an oral tablet that’s conveniently taken once a day, but it’s not used as commonly as other similar medications. You’ll also need to look out for signs and symptoms of dangerous heart rhythm changes.

Last reviewed on December 18, 2022
basics-icon

What is Toremifene (Fareston)?

What is Toremifene (Fareston) used for?

  • Metastatic HR+ breast cancer or tumors in which estrogen status is not known in postmenopausal females

How Toremifene (Fareston) works

Toremifene (Fareston) is a selective estrogen receptor modulator. Some breast cancers rely on the hormone estrogen to grow. These breast cancers are called hormone-receptor positive (HR+).

Toremifene (Fareston) works to treat HR+ breast cancer by blocking estrogen from working on breast tissue. By blocking estrogen, cancer cells don’t have the fuel they need to grow, which stops breast cancer from growing and spreading.

Drug Facts

Common BrandsFareston
Drug ClassSelective estrogen receptor modulator
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$1097.41(save 85.26%)
GoodRx discount
$161.74
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What are the side effects of Toremifene (Fareston)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Hot flashes (35%)
  • Sweating (20%)
  • Nausea (14%)
  • Vaginal discharge (13%)
  • Cataracts (10%)
  • Dry eyes (9%)

Other Side Effects

  • Changes in vision
  • Dizziness
  • Swelling
  • Vomiting

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Abnormal heart rhythm: feel your heart beating, weakness, blurred vision, lightheadedness
  • Cancers of the uterus: abnormal vaginal bleeding, vaginal discharge, or pain or pressure in the area below your belly button (pelvis)
  • Blood clots in your veins or lungs: pain or swelling in your arms or legs, trouble breathing, chest pain, fast heartbeat

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Anxiety

arm, back, or jaw pain

blurred vision

change in how much and how often you urinate

change in vaginal discharge

changes in skin color

changes in vision

changes in weight

chest pain, discomfort, tightness, or heaviness

confusion

constipation

cough

depression

dilated neck veins

dizziness, lightheadedness

dry mouth

fainting

fast, slow, or irregular heartbeat

inability to speak, incoherent speech

irregular breathing

loss of appetite

metallic taste in the tongue

muscle weakness

nausea

pain or discomfort in the arms, jaw, back, or neck

pain or feeling of pressure in the pelvis

pain, tenderness, or swelling of the foot or leg

seizures

severe or sudden headache

stomach pain

sweating

swelling of the face, fingers, feet, or lower legs

temporary blindness

tenderness, pain, swelling, warmth, skin discoloration, prominent superficial veins over the affected area

thirst

troubled breathing

unusual tiredness or weakness

vaginal bleeding

vomiting

weakness in the arm and or leg on one side of the body, sudden and severe

Incidence not known

Black, tarry stools

bleeding gums

blood in the urine or stools

chills

clay-colored stools

dark urine

fever

itching

painful or difficult urination

pinpoint red spots on the skin

rash

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

unpleasant breath odor

unusual bleeding or bruising

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Blindness

decreased vision

dry eyes

feeling of warmth

redness of the face, neck, arms, and occasionally, the upper chest

sudden sweating

sweating

Less common

Bone pain

changes in vision

double vision

eye pain

tearing

Incidence not known

Blistering, crusting, irritation, itching, or reddening of the skin

cracked, dry, or scaly skin

depression

difficulty having a bowel movement

feeling of constant movement of self or surroundings

feeling unusually cold

hair loss

lack or loss of strength

partial or slight paralysis

sensation of spinning

shakiness in the legs, arms, hands, or feet

thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Toremifene (Fareston)

thumbs-up

Pros

Available as a lower-cost generic

Only needs to be taken once a day

Can be taken with or without food

thumbs-down

Cons

Interacts with many medications

Raises the risk of dangerous changes in your heart rhythm

Requires periodic monitoring of complete blood counts, calcium levels, and liver health

pharmacist-tips

Pharmacist tips for Toremifene (Fareston)

pharmacist
  • Take toremifene (Fareston) with or without food. And try to take it around the same time every day to keep a consistent level of medication in your body.

    • Avoid taking toremifene (Fareston) with grapefruit or grapefruit juice. Doing so could cause your body to absorb more of the medication, which raises your risk for more side effects.

      • Toremifene (Fareston) interacts with many medications. Some medications can either raise your risk for more side effects or cause toremifene (Fareston) to not work as well. Always let your healthcare provider know about all the medications you take, including supplements and OTC products.

        • Toremifene (Fareston) can cause changes to your blood cell counts, calcium levels, and liver labs. Make sure to get regular lab work to check that your levels are healthy.

          faqs

          Frequently asked questions about Toremifene (Fareston)

          How long do I need to take toremifene (Fareston) for?
          It depends on your situation. For the most part, you’ll likely take toremifene (Fareston) for as long as you’re benefiting from it. Your care team will check in with you regularly and help you determine how long you’ll need to take this medication. Don’t stop taking toremifene (Fareston) without first talking with your healthcare provider.
          Can toremifene (Fareston) be used to treat any type of breast cancer?
          No. Although there are many different types of breast cancer, toremifene (Fareston) is used to treat hormone-receptor positive (HR+) metastatic breast cancer. Before treatment, your provider will perform a test to help figure out the specific type of breast cancer you have. Knowing what type of receptor your cancer has will help you provider decide what treatment is best for you.
          Can I use toremifene (Fareston) if haven’t gone through menopause yet?
          Possibly. Although toremifene (Fareston) is FDA approved to treat breast cancer in postmenopausal females, there are some studies to suggest that the medication might also be helpful for premenopausal females (those who haven’t had menopause). Studies have shown that toremifene (Fareston) works at least as well as tamoxifen (a first-choice treatment) and can be considered an alternative to treat HR+ breast cancer in premenopausal females. But your healthcare provider will work with you to determine if this medication is right for you.
          What do I do if I get hot flashes from toremifene (Fareston)?
          Hot flashes are a common side effect of toremifene (Fareston). There are many things you can do to help manage these hot flashes. You can try natural remedies like exercising, eating more fruits and vegetables, and keeping your body cool. If hot flashes continue to be bothersome, speak with your healthcare provider as there may be medications that can help or it may be recommended to switch to another treatment.
          Is toremifene (Fareston) safe in pregnancy?
          Likely not. Information from animal studies suggest that toremifene (Fareston) might cause harm to your unborn baby. If you're able to have babies, you should use non-hormonal birth control, like condoms or a diaphragm, while taking toremifene (Fareston). Talk with your provider if you're pregnant or thinking about becoming pregnant before taking this medication.
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          What are the risks and warnings for Toremifene (Fareston)?

          Toremifene (Fareston) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

          risk-warning

          Heart Rhythm problem

          • Risk factors: Long QT syndrome | Heart failure | Liver problems | Low potassium and magnesium levels | Taking other medications that cause heart rhythm problems

            Toremifene (Fareston) can affect your heart rhythm by prolonging the time period from when the heart pumps and then relaxes. This is known as QT prolongation, which can be life-threatening. Your risk for QT prolongation is higher if you have certain risk factors, including low potassium or magnesium and heart rhythm problems, or are taking other medications that also cause QT prolongation. To lower your risk, your provider will periodically monitor your heart and do certain tests to make sure your heart rhythm is normal. If you can feel your heart beating, have weakness or blurred vision, or experience lightheadedness, go to the emergency room immediately.

            risk-warning

            Liver problems

            Some people taking toremifene (Fareston) developed liver problems. These included inflammation of the liver (hepatitis), yellowing of the skin and eyes (jaundice), and non-alcoholic fatty liver disease. Your provider will monitor your liver health through lab work while you’re taking toremifene (Fareston). Let your provider know if you develop loss of appetite, nausea, vomiting, stomach pain, dark-colored urine, or yellowing of the skin and eyes. These can be symptoms of a problem with your liver.

            risk-warning

            Tumor flare

            • Risk factors: Cancer that has spread to your bones

              Particularly in people whose cancer has spread to their bones, toremifene (Fareston) can cause a temporary side effect called a tumor flare, which can happen within the first few weeks of treatment. This is when your cancer gets bigger for a short time, but it usually shrinks back soon after. During this tumor flare, you might experience pain in your muscles or have some skin redness. You might also have higher calcium levels during this time. Your provider might monitor for this through lab work. If your calcium levels get too high, your provider might have you stop taking toremifene (Fareston).

              risk-warning

              Risk of developing cancer of the uterine lining

              • Risk factors: People at high risk for endometrial cancer

                Toremifene (Fareston) can raise your risk of endometrial cancer (or cancers of the uterine lining) and other problems with your uterus (e.g., uterine polyps and enlargement of your uterus). Before you start taking toremifene (Fareston) and during treatment, your provider will perform a gynecological exam. Let your provider know if you have abnormal vaginal bleeding, vaginal discharge, or pain or pressure in the area below your belly button (pelvis). These can be signs of a problem with your uterus.

                risk-warning

                Blood clots

                • *Risk factors: Older age | Not moving much or on bed rest | History of blood clots *

                  Toremifene (Fareston) could raise your risk for blood clots in your body, that’s why it’s not recommended for people with a history of blood clots. Symptoms of a blood clot might be different depending on the location of the clot. They can include swelling, warmth, or tenderness in the legs. But more seriously, clots can lead to breathing problems and chest pain. Get medical attention right away if you have any of these symptoms.

                  risk-warning

                  Harm to unborn baby

                  Based on animal studies, toremifene (Fareston) might harm an unborn baby. Because of these risks, if you're a female who can get pregnant, you should use non-hormonal birth control, like condoms or a diaphragm, while taking toremifene (Fareston). Let your provider know right away if you become pregnant during this time.

                  dosage

                  Toremifene (Fareston) dosage forms

                  The average cost for 30 tablets of 60mg of Toremifene (Fareston) is $161.74 with a free GoodRx coupon. This is 85.26% off the average retail price of $1097.41.
                  tablet
                  Tablet
                  DosageQuantityPrice as low asPrice per unit
                  60mg30 tablets$161.74$5.39

                  Typical dosing for Toremifene (Fareston)

                  The typical dose is 60 mg taken by mouth once a day.

                  interactions

                  Interactions between Toremifene (Fareston) and other drugs

                  Toremifene (Fareston) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Toremifene (Fareston). Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                  How much does Toremifene (Fareston) cost?

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                  contraindications-icon

                  Toremifene (Fareston) contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Toremifene (Fareston) will not be safe for you to take.
                  • Heart rhythm problems (QT syndrome)

                  • Low potassium

                  • Low magnesium

                  alternatives

                  What are alternatives to Toremifene (Fareston)?

                  There are a number of medications that your doctor can prescribe in place of Toremifene (Fareston). Compare a few possible alternatives below.
                  Toremifene (Fareston)
                  Used for:
                  • Metastatic HR+ breast cancer or tumors in which estrogen status is not known in postmenopausal females

                  $161.74 Lowest GoodRx priceView Prices
                  Used for:
                  • Hormone receptor (HR)-positive, advanced or metastatic breast cancer

                  $234.50 Lowest GoodRx priceView Prices
                  Used for:
                  $24.46 Lowest GoodRx priceView Prices
                  images

                  Toremifene (Fareston) images

                  White Round Mt - Toremifene Citrate 60mg Tablet
                  This medicine is White, Round Tablet Imprinted With "Mt".White Round Mt - Toremifene Citrate 60mg Tablet

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