The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Irritation or rash at the application site (2%)
Less Common Side Effects
- Worsened rosacea bumps or pimples
- Itching
- Skin redness
- Pain at the application site
Rhofade serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Worsening heart problems: severe headaches, nosebleeds, difficulty breathing, irregular heartbeat, dizziness, feeling faint, chest pain
- Sudden glaucoma: severe eye or head pain, red eye, sudden loss of vision, blurry vision
Source: DailyMed
The following Rhofade side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Irritation at application site

