The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Reported by 1-5% of people treated clinical studies:
- Punctate keratitis (watery eyes, light sensitivity)
- Eye inflammation (pain, swelling, redness)
- Eye pain
- Eye irritation
- Dry eye
- Blurry vision
- Headache
Upneeq serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Worsening heart problems: severe headaches, nosebleeds, difficulty breathing, irregular heartbeat, dizziness, feeling faint, chest pain
- Sudden glaucoma: severe eye or head pain, red eye, sudden loss of vision, blurry vision
Source: DailyMed
The following Upneeq side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Dry eyes
- Eye irritation or itching
- Headache

