The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Signs of stress to the liver or kidney on blood tests (up to 59%)
- Abnormal electrolyte levels in the blood (up to 59%)
- Lower blood cell counts (up to 52%)
- Swelling (49%)
- Diarrhea (47%)
- Feeling very tired (46%)
- Dry mouth (43%)
- High blood pressure (41%)
- Stomach pain (34%)
- Constipation (33%)
- Rash (33%)
- Nausea (31%)
- Headache (28%)
Less Common Side Effects
- Cough
- Having trouble catching your breath
- Joint pain
- Bleeding
- Abnormal heart rhythm
Retevmo serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Liver injury: pain in the right side of the stomach, yellowing of the eyes or skin, dark or brown urine
- Lung damage: cough, shortness of breath, fever
- High blood pressure: headache, dizziness, confusion, chest pain
- Abnormal heart rhythm: chest pain, shortness of breath, dizziness, fluttering or pounding heart beat
- Severe bleeding: sudden or painful headache, changes in vision, severe stomach pain, coughing or spitting up blood
- Tumor lysis syndrome: muscle cramps, dark or brown urine, fluttering or pounding heart beat
- Allergic reaction: fever, rash, muscle, bone, or joint pain
Source: DailyMed
The following Retevmo side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
- Dry cough, shortness of breath or trouble breathing
- Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
- Increase in blood pressure
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Low thyroid levels (hypothyroidism)—unusual weakness or fatigue, increased sensitivity to cold, constipation, hair loss, dry skin, weight gain, feelings of depression
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Tumor lysis syndrome (TLS)—nausea, vomiting, diarrhea, decrease in the amount of urine, dark urine, unusual weakness or fatigue, confusion, muscle pain or cramps, fast or irregular heartbeat, joint pain
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Constipation
- Diarrhea
- Dry mouth
- Nausea
- Skin rash
- Swelling of the ankles, hands, or feet
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