The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Diarrhea (up to 29%)
- Fever (28%)
- Nausea (27%)
- Low potassium levels (22%)
- Cough (17%)
- Rash (16%)
- Swelling of the arms or legs (16%)
- Lower blood cell counts (up to 14%)
- Inflammation of mucus membranes (14%)
- Headache (14%)
- Nosebleeds (14%)
- Vomiting (13%)
Note: Side effects above reported by adults taking the tablets for prevention of fungal infection.
Less Common Side Effects
- Constipation
- Stomach pain
- Weakness
- Chills
- High blood pressure
Posaconazole serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious liver problems: nausea, vomiting, stomach pain, yellowing of the skin or whites of the eyes, flu-like symptoms
- Abnormal heart rhythm: irregular heartbeat, racing heart, chest pain, dizziness
- Changes in electrolytes: nausea, vomiting, muscle cramps, muscle weakness, abnormal heartbeat, feeling tired
Source: DailyMed
The following Posaconazole side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Abdominal or stomach pain
black, tarry stools
bloody nose
blurred vision
body aches or pain
confusion
difficult or labored breathing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
fever or chills
fruit-like breath odor
heavy non-menstrual vaginal bleeding
increased thirst or urination
irregular heartbeats
loss of voice
muscle pain, spasms, or twitching
nausea or vomiting
numbness or tingling in the hands, feet, lips, mouth, or fingertips
painful cold sores or blisters on the lips, nose, eyes, or genitals
painful or difficult urination
pounding in the ears
slow or fast heartbeat
small red or purple spots on the skin
sores, ulcers, or white spots on the lips, tongue, or inside the mouth
sweating
tender, swollen glands in the neck
tightness in the chest
trembling
trouble swallowing
unexplained weight loss
yellow eyes or skin
Less common
Fainting
irregular heartbeat, recurrent
Incidence not known
change in mental status
chest pain or discomfort
darkening of the skin
itching or skin rash
mental depression
seizures
sudden shortness of breath or troubled breathing
swelling of the eyes or eyelids
swelling of the face, fingers, feet, or lower legs
weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Acid or sour stomach
back pain
belching
difficulty having a bowel movement (stool)
muscle stiffness
pain in the joints
trouble sleeping
Less common
Bad, unusual, or unpleasant (after) taste
change in taste
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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