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Pivya

Pivya Side Effects

Matthew Kwan, PharmD CandidateConnie Zheng, PharmD
Reviewed by Matthew Kwan, PharmD Candidate, Connie Zheng, PharmD, Daisy Chau, PharmD
Last reviewed on March 24, 2026

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (4%)
  • Diarrhea (2%)

Less Common Side Effects

Pivya serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reactions: swelling of the lips, mouth, throat or tongue, difficulty breathing
  • Serious skin reactions: sore throat, cough, fever, fatigue, body aches, rash, hives, blisters, skin reddening or peeling
  • Infectious (C. difficile-related) diarrhea: fever, nausea, foul-smelling diarrhea, frequent bowel movements (even up to 15 times per day)
  • Low carnitine levels: muscle weakness, fatigue, irregular heartbeat, low blood sugar (e.g., shakiness, sweating, dizziness)
  • Serious nerve-related problem (acute porphyria): anxiety, confusion, seizures, stomach or limb pain, nausea and vomiting, dark or reddish-brown urine, muscle weakness

Source: FDA

The following Pivya side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Low carnitine level —low muscle tone, muscle weakness, fatigue, irritability, tremors or shaking, anxiety, sweating, confusion, shortness of breath, swelling of the ankles, feet, or hands
  • Rash, fever, and swollen lymph nodes
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth
  • Severe diarrhea, fever
  • Unusual vaginal discharge, itching, or odor

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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