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Padcev

Padcev Dosage

Julia Lee, PharmD, BCOPCydnee Ng, PharmD
Reviewed by Julia Lee, PharmD, BCOP, Cydnee Ng, PharmD
Last reviewed on November 10, 2025

Typical dosage for Padcev

Your oncology care team will calculate your Padcev dose based on your weight. The typical dose is 1.25 mg/kg as an infusion through the vein (IV). The highest dose you can get for each infusion is 125 mg.

Your Padcev dosing schedule depends on whether it's used by itself or together with other cancer treatments.

  • When using Padcev by itself: Your Padcev infusions will be on day 1, 8, and 15 of each 28-day treatment cycle.
  • When using Padcev together with Keytruda (pembrolizumab): Your Padcev infusions will be on day 1 and 8 of each 21-day treatment cycle.
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