Oxytrol for Women (oxybutynin) is an over-the-counter anticholinergic medication. It's a patch that's applied onto the skin and is used to treat urinary incontinence (overactive bladder) in women. The patch is applied every 4 days. Common side effects include itchiness and redness where you placed the patch on the skin and dry mouth.
Note: Oxytrol for Women is specifically for women. There's a prescription-only version for men called Oxytrol.
Overactive bladder in women
Oxytrol for Women (oxybutynin) is an anticholinergic medication. It's also known as an antimuscarinic.
Oxytrol for Women (oxybutynin) works by blocking a chemical in the body called acetylcholine from attaching to muscarinic receptors in the bladder. This causes your bladder muscles to relax, which helps with bladder control and lowering the urge or need to urinate.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Bladder pain
blistering, crusting, irritation, itching, or reddening of the skin
bloody or cloudy urine
burning, skin rash, swelling, soreness, redness, pain, itching, or irritation at the application site
cracked, dry, or scaly skin
difficult, burning, or painful urination
frequent urge to urinate
lower back or side pain
unusually warm skin
Incidence not known
Confusion as to time, place, or person
holding false beliefs that cannot be changed by fact
seeing, hearing, or feeling things that are not there
unusual excitement, nervousness, or restlessness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Back pain
bloated feeling
changes in vision
excess air or gas in the stomach or intestines
feeling of fullness
muscle aches
passing gas
sleepiness or unusual drowsiness
Incidence not known
Forgetfulness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Available over the counter
Applied every 4 days
Typically has less side effects than oxybutynin pills that are taken by mouth
Might have skin irritation and itching
Not meant to be used by men or children
Not available as a lower-cost generic
Talk to a healthcare professional before you use Oxytrol for Women (oxybutynin) if you have symptoms of diabetes (e.g., feeling very thirsty or hungry), unexplained weight loss, or liver or kidney problems. It's possible that frequent urination is a symptom of other health problems besides overactive bladder.
Don't use Oxytrol for Women (oxybutynin) without talking to your primary care provider first if you're currently taking other prescription medications for overactive bladder, antibiotics, or antifungal medications. Taking certain types of these medications with Oxytrol for Women (oxybutynin) can raise the risk for side effects.
Oxytrol for Women (oxybutynin) can make you dizzy, sleepy, and confused. It might also cause blurry vision. Don't drive, operate machinery, or do anything that requires concentration until you know how this medication affects you.
It's best not to drink alcohol while you're using Oxytrol for Women (oxybutynin). Alcohol can worsen side effects like dizziness and sleepiness.
Stay hydrated while you're taking Oxytrol for Women (oxybutynin) to help with dry mouth from the medication. Drinking water also helps prevent your body from overheating easily (especially when it's hot). This medication can cause your body to make less saliva and sweat. Sweating less makes it hard for your body to cool down.
Stop using Oxytrol for Women (oxybutynin) and contact your primary care provider if your overactive bladder symptoms don't improve after 2 weeks, if they worsen, or if you have any new symptoms. Also let your primary care provider know if you feel that you can't empty your bladder. They can examine you and see what's going on.
Stop using Oxytrol for Women (oxybutynin) and get medical help if you have severe redness, itchiness, or blistering where you put the patch. Also get medical help right away if you have any other allergic reaction (e.g., trouble breathing).
How to use Oxytrol for Women (oxybutynin):
Apply 1 Oxytrol for Women (oxybutynin) patch onto the skin every 4 days. Place each new patch on a different area of the body to help prevent skin irritation. Don't wear more than 1 patch at a time.
How to apply Oxytrol for Women (oxybutynin): Apply the sticky side of the patch onto the skin at your stomach, hips, or buttocks. Press your hand over the patch so it sticks well. Wear the patch under your clothes so it's protected from light.
Make sure the skin where you stick Oxytrol for Women (oxybutynin) onto is clean, dry, and smooth. Don't apply the patch onto skin that's irritated, damaged with cuts or scrapes, or oily. Also don't place the patch onto skin that has oils, lotions, or powders on it because the patch might not stick well.
If your Oxytrol for Women (oxybutynin) patch falls off, you can try to press it back onto the same spot on the skin. But if the patch doesn't stay on at all, replace it with a new patch on a different area of skin. Continue with your normal patch replacement schedule.
When you take off the patch, slowly peel it off from the skin and fold it in half so the sticky sides come together. Throw the folded patch in a trash bin where children and pets can't get into. Used patches still contain medication that can be harmful for children and pets if it accidentally gets on their skin or in their mouth.
Oxytrol for Women (oxybutynin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Taking other medications that cause nervous system side effects
Oxytrol for Women (oxybutynin) can cause sleepiness, dizziness, and confusion. These side effects can be more intense if you drink alcohol while you're taking Oxytrol for Women (oxybutynin). They can also be worse if you take Oxytrol for Women (oxybutynin) with other medications that can make you tired, such as certain antihistamines and muscle relaxers.
Let your primary care provider know if you have any sleepiness, dizziness, or confusion that negatively affect your usual daily activities while you're taking Oxytrol for Women (oxybutynin). Don't drive or do any activities that require a lot of attention until you know how Oxytrol for Women (oxybutynin) makes you feel.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
3.9mg | 16 patches | $54.37 | $3.40 |
Each patch provides 3.9 mg of oxybutynin per day.
Apply 1 patch to dry, clean skin on your stomach, hips, or buttocks every 4 days. Make sure that you take off the used patch before you apply a new one onto the skin.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Have signs of a urinary tract infection (UTI), such as pain or burning when urinating, bloody urine, unexplained lower back pain or side pain, cloudy or foul-smelling urine
Only have bathroom accidents when you cough, sneeze, or laugh
Male
Younger than 18 years old
Can't urinate or completely empty your bladder (urinary retention), such as with an enlarged prostate
Stomach or intestinal blockage
Overactive bladder in women
Overactive bladder in adults - tablets only
Neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem) in children ages 2 years and older - liquid only
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Allergan, Inc. (2024). Oxytrol- oxybutynin patch [package insert]. DailyMed.
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National Institute of Diabetes and Digestive and Kidney Diseases. (2019). Definition & facts of urinary retention.
Sam, C., et al. (2023). Physiology, acetylcholine. StatPearls.
Wyman, J. F., et al. (2009). Practical aspects of lifestyle modifications and behavioural interventions in the treatment of overactive bladder and urgency urinary incontinence. International Journal of Clinical Practice.
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