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Oxycodone/Ibuprofen Coupon - Oxycodone/Ibuprofen 5mg/400mg tablet

oxycodone / ibuprofen

Generic Combunox
Used for Pain

Oxycodone/ibuprofen is a combination medication used to treat moderate-to-severe pain. Because it has a high risk of dependency, misuse, and overdose, it should only be used for a short period of time. This medication is no longer available because it was discontinued in the United States.

Reviewed by:
reviewerShifali Patel, PharmD
reviewerAshley Wong, PharmD
Last reviewed on January 10, 2022
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What is Oxycodone/ibuprofen?

Drug facts

Common BrandsCombunox(brand no longer available)
Drug ClassOpioid / NSAID
Controlled Substance ClassificationSchedule II
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Common questions about Oxycodone/Ibuprofen

Common questions about Oxycodone/Ibuprofen

Oxycodone/Ibuprofen is a combination medication that treats moderate-to-severe pain. Oxycodone is an opioid that binds to certain parts of your brain, called mu-opioid receptors, to change how you react to pain. This helps decrease how much pain you feel. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves pain, fever, and swelling. Oxycodone/Ibuprofen should only be used for a short period of time (maximum of 7 days) because it has serious risks of stomach bleeds, stomach ulcers, abuse, misuse, and overdose.

No. Oxycodone/Ibuprofen is no longer available as a brand or generic medication in the United States.

It's unclear why Oxycodone/Ibuprofen was discontinued. According to the U.S. Food and Drug Administration (the FDA), Oxycodone/Ibuprofen wasn't discontinued because it was unsafe or didn't work well. It's possible that it was removed from the market due to the availability of newer and safer combination pain medications.

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Oxycodone/ibuprofen dosage

Typical dosage for Oxycodone/ibuprofen

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Interactions between Oxycodone/ibuprofen and other drugs

Oxycodone/ibuprofen may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Oxycodone/ibuprofen. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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