Osmoprep

Although rare, bowel preps that contain sodium phosphate, including OsmoPrep (sodium phosphate), have caused sudden kidney damage called acute phosphate nephropathy. This typically happens within days after taking OsmoPrep (sodium phosphate), but can sometimes happen months later. Sometimes, the damage is permanent and might require long-term dialysis treatment. You're at higher risk for kidney damage if you're also taking other medications that affect your kidneys, such as diuretics (water pills), angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs). It’s important to follow your provider’s directions on how to properly take this medication. Drink enough water before, during, and after taking OsmoPrep (sodium phosphate) to avoid getting dehydrated. Don’t take any other sodium phosphate medications or enema products with this bowel prep. Let your provider know right away if you feel tired, drowsy, have a hard time urinating, or have swelling in your legs and feet.

OsmoPrep (sodium phosphate) can cause a lot of fluid loss (dehydration) and an imbalance in body salts (electrolytes). This can lead to problems such as abnormal heartbeat, seizures, and kidney problems. If you experience a lot of vomiting or signs of dehydration, let your provider know immediately. They might need to order lab work to check your electrolytes and kidney function.

Although rare, OsmoPrep (sodium phosphate) might cause changes in your heartbeat because it can affect the balance of electrolytes in your body. Your risk of heart problems is higher if you're taking other medications that affect your heartbeat. If you have a history of heart problems, tell your provider before starting OsmoPrep (sodium phosphate) because they might need to check your heart before and after you use this medication.

Taking OsmoPrep (sodium phosphate) can affect the balance of fluids and electrolytes in your body and can raise your risk for seizures, even if you've never had seizures before. Your risk is higher if you're also taking other medications that might cause seizures, such as tricyclic antidepressants. Be careful using this medication if you have a history of seizures. Get medical help right away if you feel like fainting.

Osmotic laxatives, such as OsmoPrep (sodium phosphate), can cause damage in your bowels. Let your provider know if you have stomach ulcers, blockage, or inflammation before taking OsmoPrep (sodium phosphate), and report any signs of severe stomach pain or blood in your stools.