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Onivyde

Onivyde Dosage

Julia Lee, PharmD, BCOPCydnee Ng, PharmD
Reviewed by Julia Lee, PharmD, BCOP, Cydnee Ng, PharmD
Last reviewed on October 9, 2025

Typical dosage for Onivyde

Your oncology team will determine your dose based on your body surface area (BSA). It’s measured in units of m² and uses your height and weight.

  • First-choice treatment of metastatic pancreatic cancer: The typical dose is 50 mg/m² given as an infusion through the vein (IV) once every 2 weeks. Onivyde is given together with oxaliplatin, 5-fluorouracil, and leucovorin injection. This treatment regimen is called NALIRIFOX.

  • Next-choice treatment of metastatic pancreatic cancer after gemcitabine-based therapy: The typical dose is 70 mg/m² given as an IV infusion once every 2 weeks. Your dose might be lower if you have certain genetics. Onivyde is given together with 5-fluorouracil and leucovorin injection.

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