Mresvia
MRESVIA is an mRNA vaccine that's used to protect adults 60 years and older from illness caused by respiratory syncytial virus (RSV). This vaccine is injected into the muscle by a trained healthcare professional (HCP), and you only need to get one dose. Some potential side effects of the MRESVIA RSV vaccine include pain at the injection site, tiredness, headache, and muscle pain.
What is MRESVIA?
What is MRESVIA used for?
- Prevention of illness caused by respiratory syncytial virus (RSV)
How MRESVIA works
MRESVIA is an mRNA vaccine. This vaccine contains lab-made mRNA (genetic information) that teaches your body to make a part of a protein found on RSV.
Your immune system recognizes that this harmless protein doesn't belong in your body. This causes your immune system to make antibodies against the protein. The antibodies tell other immune cells to get rid of it.
Your immune system learns what the RSV protein looks like. So when you get infected with RSV, your immune system is ready to fight and protect you from infection.
Drug facts
Side effects of MRESVIA
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Pain at the injection site (56%)
- Feeling tired (31%)
- Headache (27%)
- Muscle pain (26%)
- Joint pain (22%)
- Underarm swelling or tenderness (15%)
- Chills (12%)
Less Common Side Effects
- Redness at the injection site
- Swelling at the injection site
- Fever
- Nausea or vomiting
MRESVIA serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: hives; difficulty breathing; swelling of the face, lips, tongue, or throat
The following MRESVIA side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Feeling faint or lightheaded
- Weakness and tingling in the feet and legs that spreads to upper body
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- General discomfort and fatigue
- Headache
- Muscle pain
- Pain, redness, or irritation at injection site
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Pros and cons of MRESVIA
Pros
- Given as a single dose
- Lowers the risk of RSV-related illness by up to 84% in people 60 years and older
- Offers protection against RSV-A and RSV-B, two types of the virus
Cons
- Only available as an injection, which might be uncomfortable
- Can cause temporary side effects such as headache and muscle aches
- Not approved for people younger than 60 years old
Pharmacist tips for MRESVIA
- Discuss your full medical history with your primary care provider before you get vaccinated with MRESVIA. This vaccine might not work as well for you if you have conditions (or are taking medications) that weaken your immune system.
- For MRESVIA to be most effective, you should get it during late summer or early fall, just before the start of RSV season. Ask your primary care provider about the best time for you to get your vaccine.
- After getting the MRESVIA vaccine, stay seated for a few minutes. Vaccines that are injected, like MRESVIA, can sometimes cause fainting.
- Share your vaccination record with a healthcare professional so they can help you get up to date with all of your vaccines.
- Tell your primary care provider or pharmacist if you experience any side effects from MRESVIA. You can also report side effects to the Vaccine Adverse Event Reporting System at 1-800-822-7967 and www.vaers.hhs.gov.
Common questions about MRESVIA
According to the manufacturer Moderna, MRESVIA is expected to be available by the 2024/2025 respiratory virus season. Check with your primary care provider or local pharmacy to find out more information.
No, MRESVIA isn't a live vaccine. It doesn't contain any live virus. It's an mRNA vaccine that teaches your body to make a protein that's found on RSV, which causes your immune system to build antibodies against it for protection.
During a clinical study that included over 35,000 older adults, researchers found that MRESVIA was around 84% effective at preventing illness from RSV infection. The vaccine protected people against both types of RSV (A and B).
The CDC recommends that older adults get their RSV vaccine in the late summer or early fall. This is because RSV typically spreads in the fall and winter. Ask your primary care provider about whether an RSV vaccination is appropriate for you, and if so, when you should get it.
All three are RSV vaccines that are FDA approved for people ages 60 years and older. But Abrysvo is also approved for people between 32 to 36 weeks of pregnancy. MRESVIA, Arexvy, and Abrysvo are all given as an injection in the muscle. They each work slightly differently. Talk to your primary care provider about which RSV vaccine might be best for you.
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Risks and warnings for MRESVIA
MRESVIA can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Severe allergic reaction
Although rare, it's possible for MRESVIA to cause a severe allergic reaction. Get medical help right away if you experience tightness in your chest; trouble breathing; skin rash; or swelling in your lips, tongue, throat, or face after you get your MRESVIA shot.
Fainting
Some people might feel faint after they get injectable vaccines like MRESVIA. To lower your risk of fainting, stay seated for a while after your vaccination and stand up slowly to make sure you don't fall.
Vaccine might not work as well for people with a weakened immune system
- Risk factors: Medical conditions that weaken the immune system | Taking medications that weaken your immune system
MRESVIA might not work as well for people with a weakened immune system. Talk to your primary care provider before you get vaccinated with MRESVIA if you have a medical condition that lowers the immune system, such as human immunodeficiency virus (HIV) or cancer. Also speak with your primary care provider if you take medications that weaken your immune system, like high-dose corticosteroids or transplant medications).
MRESVIA dosage
Carton| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 0.5ml prefilled syringe | 1 carton | $292.36 | $292.36 |
Typical dosage for MRESVIA
Adults ages 60 years and older: The typical dose is 0.5 mL injected into the muscle by a healthcare professional.
How much does MRESVIA cost?
$292.36
What are alternatives to MRESVIA?
Prevention of serious lung infections caused by respiratory syncytial virus (RSV) in:
Prevention of serious lung infections caused by respiratory syncytial virus (RSV) in:
News about MRESVIA
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