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Abrysvo Coupon - Abrysvo 1 dose kit

Abrysvo

RSV vaccine
Used for RSV

Abrysvo (RSV vaccine) is a vaccine that helps lower your risk of getting serious lung infections caused by respiratory syncytial virus (RSV). It's FDA approved for adults 60 years and older, and adults 18 to 59 years who have a higher risk of getting seriously ill from RSV. It's also approved for pregnant mothers between 32 and 36 weeks gestation to help protect their babies from RSV after birth. Abrysvo (RSV vaccine) is given as a single injection into the muscle. Common side effects include tiredness, headache, and injection site reactions like pain, swelling, or redness.

Reviewed by:Last reviewed on August 11, 2025
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What is Abrysvo (RSV vaccine)?

What is Abrysvo (RSV vaccine) used for?

Prevention of serious lung infections caused by respiratory syncytial virus (RSV) in:

  • Adults 60 years and older
  • Adults 18 to 59 years old who have a higher risk of illness due to RSV
  • Pregnant mothers between 32 to 36 weeks gestation

How Abrysvo (RSV vaccine) works

Abrysvo (RSV vaccine) is a recombinant protein vaccine. It contains proteins from the RSV virus that trigger your immune system to make antibodies to fight the virus.

If you’re exposed to RSV later, these antibodies can stop the virus from infecting your lungs. And if you get the vaccine during pregnancy, your body can pass some of these antibodies to your baby before they are born. This helps protect your newborn from RSV after birth.

When does Abrysvo (RSV vaccine) start working?Time passed since treatment started:
HOURS
DAYS
WEEKS
Full effect
MONTHS

Drug facts

Common BrandsAbrysvo
Drug ClassVaccine
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Side effects of Abrysvo (RSV vaccine)

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

18 to 59 years old:

  • Tiredness (37%)
  • Pain at injection site (35%)
  • Headache (28%)
  • Muscle pain (24%)
  • Diarrhea (15%)
  • Joint pain (12%)
  • Nausea (12%)

60 years and older:

  • Tiredness (16%)
  • Headache (13%)
  • Pain at injection site (11%)
  • Muscle pain (10%)

Pregnant mothers:

  • Tiredness (46%)
  • Pain at injection site (41%)
  • Headache (31%)
  • Muscle pain (27%)
  • Nausea (20%)

Less Common Side Effects

  • Redness at the injection site
  • Swelling at the injection site
  • Fever
  • Joint pain
  • Diarrhea
  • Vomiting

Abrysvo (RSV vaccine) serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: rash, hives, racing heart, trouble breathing, swelling of the face or tongue
When do Abrysvo (RSV vaccine) possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Pain at injection site
Tiredness
Headache
Muscle pain
Nausea

Source: DailyMed

The following Abrysvo (RSV vaccine) side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Feeling faint or lightheaded
  • Weakness and tingling in the feet and legs that spreads to upper body

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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Pros and cons of Abrysvo (RSV vaccine)

Pros

  • Only need one dose
  • Protects both adults and newborns from serious RSV illness
  • Can be given with other vaccines

Cons

  • Injection might be uncomfortable
  • Not approved for people under 18 years old
  • Common side effects include tiredness and headache
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Pharmacist tips for Abrysvo (RSV vaccine)

pharmacist
  • Abrysvo (RSV vaccine) is given as a one-time shot into the muscle. You don't need a second dose at this time.
  • Injectable vaccines like Abrysvo (RSV vaccine) can sometimes make people feel lightheaded or faint. After getting the shot, stay seated for some time and stand up slowly to make sure you feel okay.
  • After getting Abrysvo (RSV vaccine), you might experience redness, swelling, or pain where the shot was given. This is called an injection site reaction and usually goes away in a few days.
  • If you notice any unusual or serious side effects after getting Abrysvo (RSV vaccine), tell your healthcare professional right away. You can also report side effects to the Vaccine Adverse Event Reporting System (VAERS) at 1-800-822-7967 or https://vaers.hhs.gov/.
  • If you have a weakened immune system or take medications that weaken your immune system, Abrysvo (RSV vaccine) might not work as well for you. Talk to your healthcare professional about what this means for your protection against RSV.
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Common questions about Abrysvo (RSV vaccine)

No, Abrysvo (RSV vaccine) isn't an mRNA vaccine. It's a recombinant protein vaccine, which means it contains pieces of the RSV virus (proteins) that help your immune system recognize and fight the virus. These proteins trigger your body to make antibodies. mRNA vaccines work differently —they use a small piece of genetic material (mRNA) to teach your cells to make certain proteins that trigger your immune system to develop a response against the virus.

Yes, Abrysvo (RSV vaccine) is generally considered safe for people who are eligible to receive it. But like all vaccines, it can cause some side effects. Common side effects include pain at the injection site, headache, muscle pain, and nausea. In rare cases, Abrysvo (RSV vaccine) can cause more serious reactions, such as Guillain-Barré syndrome, preterm birth, or allergic reactions. Talk to your healthcare professional about all of the risks and benefits of getting this vaccine.

Abrysvo (RSV vaccine) is available at many pharmacies, hospitals, and medical clinics, and it's given by a healthcare professional. To find out where you can get the vaccine near you, talk to your primary care provider or pharmacist. They can help you schedule an appointment or check availability in your area.

Most side effects from Abrysvo (RSV vaccine) are mild and usually go away within a couple of days. For example, pain and redness around the injection site should improve shortly after getting the shot. If your symptoms feel severe or get worse, contact your healthcare professional for guidance.

Abrysvo (RSV vaccine) is FDA approved for adults 60 years and older, adults 18 to 59 years at a higher risk for illness, and pregnant mothers between 32 and 36 weeks gestation. While RSV usually causes mild, cold-like symptoms, it can lead to serious illness in older adults, people with weakened immune systems, and infants, who are at a higher risk for severe RSV complications. Currently, the CDC recommends one dose of Abrysvo (RSV vaccine). Talk with your primary care provider or OB-GYN to see if this vaccine is right for you.

Only one dose of Abrysvo (RSV vaccine) is recommended. If you're pregnant, the CDC advises getting the vaccine between 32 and 36 weeks of pregnancy. For others, your healthcare professional might suggest getting your shot in late summer or early fall, since this is the time before the RSV virus is most active. Be sure to discuss the best timing to get your RSV vaccine with your healthcare professional.

Yes, Abrysvo (RSV vaccine) isn't an annual vaccine which means you only need to get one dose. Studies are ongoing to see if additional doses are needed over time.

Both Abrysvo and Arexvy are FDA-approved RSV vaccines, but they're approved for slightly different groups. Both are approved for adults 60 years and older, but only Abrysvo is also approved for pregnant mothers between 32 to 36 weeks, and for adults 18 to 59 years old who are at a higher risk of illness due to RSV. In comparison, Arexvy is approved for adults 50 to 59 years old with a higher risk. Right now, only one dose is recommended for either vaccine. Talk to your primary care provider to learn more about the differences between these two vaccines.

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Risks and warnings for Abrysvo (RSV vaccine)

Abrysvo (RSV vaccine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Guillain‑Barré syndrome

Although rare, Abrysvo (RSV vaccine) might raise your risk for a condition called Guillain‑Barré syndrome (GBS), where your immune system attacks your nerves. This is most likely to happen during the first 42 days after getting the vaccine. Call your healthcare professional right away if you experience symptoms like tingling or muscle weakness in your legs or arms.

Potential risk of preterm (early) birth

In studies, more preterm (early) births were seen in pregnant mothers who got Abrysvo (RSV vaccine) compared to those who didn't. It’s not clear if the vaccine caused this or if it was due to something else. To help lower this possible risk, your healthcare professional will give you Abrysvo (RSV vaccine) between 32 and 36 weeks of pregnancy.

Severe allergic reaction

Although rare, it's possible for Abrysvo (RSV vaccine) to cause a severe allergic reaction. Get medical help right away if you experience skin rash, tightness in your chest, trouble breathing, or swelling in your lips, tongue, throat, or face after receiving this vaccine.

Fainting

Injectable vaccines like Abrysvo (RSV vaccine) can cause some people to faint afterwards. Stay seated for a while after getting your vaccine, and stand up slowly to make sure you don't fall if you feel faint or dizzy.

Weaker vaccine protection

  • Risk factors: Medical conditions that weaken the immune system | Taking medications that weaken your immune system

Abrysvo (RSV vaccine) might not work as well if you have a weakened immune system. If you have certain medical conditions like human immunodeficiency virus (HIV), cancer) or take medications that weaken your immune system — such as high-dose corticosteroids, transplant medications, cancer treatments) — talk to your healthcare professional first before getting Abrysvo (RSV vaccine). They can help you decide if the vaccine is right for you.

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Abrysvo (RSV vaccine) dosage

The average cost for 1 kit of 1 dose of Abrysvo (RSV vaccine) is $323.79 with a free GoodRx coupon. This is 8.00% off the average retail price of $351.94.
kitKit
DosageQuantityPrice as low asPrice per unit
1 dose1 kit$323.79$323.79

Typical dosage for Abrysvo (RSV vaccine)

The typical dose is 0.5 mL injected into the muscle by a healthcare professional.

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How much does Abrysvo (RSV vaccine) cost?

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What are alternatives to Abrysvo (RSV vaccine)?

There are a number of medications that your doctor can prescribe in place of Abrysvo (RSV vaccine). Compare a few possible alternatives below.
Abrysvo (RSV vaccine)
Used for:

Prevention of serious lung infections caused by respiratory syncytial virus (RSV) in:

  • Adults 60 years and older
  • Adults 18 to 59 years old who have a higher risk of illness due to RSV
  • Pregnant mothers between 32 to 36 weeks gestation
$323.79Lowest GoodRx priceView prices
Used for:

Prevention of serious lung infections caused by respiratory syncytial virus (RSV) in:

  • Adults 60 years and older
  • Adults 50 to 59 years old who have a higher risk of illness due to RSV
$311.12Lowest GoodRx priceView prices
Used for:
$292.36Lowest GoodRx priceView prices
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Abrysvo (RSV vaccine) images

white - ABRYSVO Powder for Injection
This medicine is White Kit.white - ABRYSVO Powder for Injection
white - ABRYSVO Powder for Injection
This medicine is White Kit.white - ABRYSVO Powder for Injection

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References

Best studies we found

Centers for Disease Control and Prevention. (2025). How RSV Spreads.

Centers for Disease Control and Prevention. (2025). RSV Vaccine Guidance for Adults.

Centers for Disease Control and Prevention. (2025). Vaccines for Adults.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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