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Malarone

Malarone Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on April 3, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Stomach pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Low appetite
  • Headache
  • Weakness
  • Dizziness

Less Common Side Effects

  • Cough
  • Mouth sores
  • Vivid dreams

Malarone serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, confusion, dark or brown urine

Source: DailyMed

The following Malarone side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Incidence not known

Blistering, peeling, loosening of skin

chills

convulsions

difficulty swallowing

fast heartbeat

hives or welts

increased sensitivity of skin to sunlight

itching, redness or other discoloration of skin

joint or muscle pain

large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs

loss of bladder control

muscle spasm or jerking of all extremities

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rash

red, irritated eyes

red skin lesions, often with a purple center

seeing, hearing, or feeling things that are not there

severe mental changes

severe sunburn

shortness of breath

skin rash

sores, ulcers or white spots in mouth or on lips

sudden loss of consciousness

tightness in chest

unusual tiredness or weakness

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal pain

back pain

coughing

diarrhea

dreams

fever

headache

itching skin

lack of or loss of strength

nausea

muscle pain

sore throat

sores in mouth

sneezing

vomiting

Less common

Acid or sour stomach

belching

blurred or loss of vision

disturbed color perception

dizziness

double vision

flu like symptoms

halos around lights

heartburn

indigestion

loss of appetite

night blindness

overbright appearance of lights

sleeplessness

stomach discomfort, upset or pain

trouble sleeping

tunnel vision

unable to sleep

weight loss

Rare

Discouragement

fear

feeling sad or empty

irritability

lack of appetite

loss of interest or pleasure

nervousness

trouble concentrating

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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