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Quinine

Quinine Side Effects

Robert Chad Hakim, PharmD, BCCCPKristianne Hannemann, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Kristianne Hannemann, PharmD
Last reviewed on July 24, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache
  • Sweating
  • Ringing in the ears
  • Hearing loss
  • Dizziness
  • Blurry vision
  • Changes in how you see color

Less Common Side Effects

  • Nausea
  • Stomach pain
  • Vomiting
  • Diarrhea

Quinine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Hemolytic anemia (low red blood cell count): tiredness, dizziness, weakness, high heart rate, yellowing of the skin or eyes, dark-colored urine
  • Bleeding: blood in your urine or stool, unexplained bruising, bleeding that takes longer than usual to stop
  • Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
  • Serious allergic and skin reactions: sore throat, fever, fatigue, rash, hives, painful blisters, skin reddening, skin peeling, difficulty breathing, itching, fast heartbeat, tightness in the throat, swelling in the face or tongue
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Source: DailyMed

The following Quinine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blurred vision

change in color vision

changes in behavior

confusion

diarrhea

hearing loss

nausea

ringing in the ears

stomach cramps or pain

vomiting

Less common

Anxiety

behavior change, similar to drunkenness

black, tarry stools

bloody urine

blurred vision or change in vision

chills

cold sweats

confusion

cool pale skin

cough

difficulty concentrating

drowsiness

excessive hunger

fast heartbeat

fever

headache

hoarseness

loss of consciousness

lower back or side pain

nervousness

nightmares

painful or difficult urination

pinpoint red spots on the skin

restless sleep

seizures

shakiness

slurred speech

sore throat

unusual bleeding or bruising

unusual tiredness or weakness

Rare

Difficulty breathing or swallowing

disturbed color perception

double vision

hives

increased sweating

muscle aches

night blindness

reddening of the skin, especially around ears

ringing or buzzing in the ears

swelling of the eyes, face, inside of the nose, fingers, feet, or lower legs

Incidence not known

Back, leg, or stomach pains

bleeding gums

bleeding under the skin

blindness

blistering, peeling, or loosening of the skin

bloody nose

blue-yellow color blindness

change in mental status

chest pain

cold sweats

confusion

cool, pale skin

cough

dark urine

decreased frequency or amount of urine

decreased vision

depression

diarrhea

difficulty breathing

difficulty in moving

difficulty speaking

dizziness

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

eye pain

fainting

fast, pounding, or irregular heartbeat or pulse

general body swelling

general feeling of discomfort, illness, or weakness

hoarseness

heavier menstrual periods

hoarseness

increased hunger

increased or decreased urination

increased sensitivity of the skin to sunlight

increased thirst

irregular heartbeat, recurrent

irritation

itching, skin rash

joint pain, stiffness, or swelling

light-colored stools

loss of appetite

muscle cramps, weakness, or stiffness

nervousness

nightmares

nosebleeds

painful or difficult urination

pale color of the skin

pale skin

red skin lesions, often with a purple center

red, irritated eyes

redness or other discoloration of the skin

severe

sunburn

sores, ulcers, or white spots in the mouth or on the lips

tightness in the chest

troubled swallowing

upper right abdominal pain

weakness

weight gain

yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of an overdose

Blindness

blurred vision or change in vision

chest pain

dizziness

double vision

fainting

lightheadedness

rapid or irregular heartbeat

sleepiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Feeling of warmth

heartburn

lack or loss of strength

pain or burning in the throat

problems with speech or speaking

restlessness

thoughts or attempts of killing oneself tremors

unsteadiness, trembling, or other problems with muscle control or coordination

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

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