Joenja

If you miss your Joenja (leniolisib) dose by more than six hours or vomit more than one hour after taking the medication, skip that dose. Then, wait to take your next dose at the regular time you take your medication. But if you vomit within one hour of taking Joenja (leniolisib), you should take another dose as soon as possible. To avoid missing doses, try placing your medication in an area where you’ll see it every day. You can also set a reminder on your phone or use a pill organizer to help you remember to take Joenja (leniolisib).

If your skin gets dry or itchy while you’re taking Joenja (leniolisib), try keeping it moisturized throughout the day. To help add moisture to your skin, you can apply a moisturizing lotion to your skin during the day or try using a humidifier in your home. There are many over-the-counter (OTC) products, like skin moisturizers (Vaseline, Aquaphor) and hydrocortisone, that can help with skin irritation as well. Talk to your pharmacist or healthcare provider about which OTC product might be right for you. They can also recommend other ways to help treat or prevent dry, itchy, or irritated skin.

So far, one small clinical study showed that people who took Joenja (leniolisib) for 3 months noted improvements in immune-related symptoms of APDS. For example, people who took Joenja (leniolisib) had a larger rise in the amount of certain white blood cells in their body than people who took placebo. Their lymph nodes also shrunk more noticeably than those of people who took placebo. These improvements are important because people with APDS typically have low numbers of white blood cells, which raise their risk of infection. They can also have swollen lymph nodes, which can be a sign of infection. In fact, it’s common for people with APDS to get ear, sinus, upper respiratory tract, and lung infections that won’t go away or come back often. It’s not known whether Joenja (leniolisib) helps with other symptoms of APDS, such as long-term coughing and stomach pain.

Maybe. It’s best to get all routine or recommended vaccinations before starting Joenja (leniolisib). And once you start treatment, let your healthcare provider know that you’re taking this medication before getting any vaccines. They can discuss with you whether it’s okay for you to get vaccinated. Some vaccines, such as live vaccines, might not work as well if you get them while you’re taking Joenja (leniolisib). These vaccines include the measles, mumps, and rubella vaccine (MMR) and varicella (chicken pox) vaccine. It’s not known whether other vaccines, such as influenza (flu) and Tdap (tetanus, diphtheria, and pertussis), interact with Joenja (leniolisib).