Invega Trinza

Older adults who also have dementia sometimes have some of the symptoms of schizophrenia, like hallucinations and delusions. This is called dementia-related psychosis, and it shouldn't be treated with Invega Trinza (paliperidone). If Invega Trinza (paliperidone) is used for dementia-related psychosis, it can cause death. The cause of death is typically from heart problems, stroke, or infections. Let your provider know if you or your loved one has dementia before starting Invega Trinza (paliperidone).

Invega Trinza (paliperidone) can cause neuroleptic malignant syndrome (NMS), which is a rare but serious condition that can be life-threatening. Be careful using Invega Trinza (paliperidone) if you're also taking other medications that might cause NMS. Symptoms include a very high fever, stiff muscles, problems thinking clearly, a very fast or uneven heartbeat, and sweating. Stop taking Invega Trinza (paliperidone) and get medical attention right away if you experience these symptoms.

Although rare, Invega Trinza (paliperidone) can affect your heart rhythm by lengthening the time period from when the heart pumps and then relaxes. This is known as QT prolongation and it can be life-threatening. Your risk for QT prolongation is higher if you have any of the risk factors listed above. Make sure to tell your provider about all the medications you're taking and don't start any new medications while taking Invega Trinza (paliperidone) without talking to your provider or pharmacist first. People who were born with QT prolongation or have a history of arrhythmias should avoid taking Invega Trinza (paliperidone). If you feel your chest pounding, have trouble breathing, chest pain, or feel faint or lightheaded while taking Invega Trinza (paliperidone), call 911 right away.

Invega Trinza (paliperidone) can cause uncontrolled and possibly permanent muscle movements in the tongue, face, mouth, lips, neck, hands, arms, legs, and feet (tardive dyskinesia). To lower your risk of tardive dyskinesia, your provider will have you take the lowest dose that treats your symptoms. Get medical help right away if you notice any unusual movements you can't control. This side effect can sometimes occur even after you stop the medication.

Invega Trinza (paliperidone) can raise your blood sugar levels. Rarely, it can reach dangerous levels resulting in coma or death. Let your provider know if you have symptoms of high blood sugar, such as feeling very hungry or thirsty, urinating more often, stomach pain, weakness, or fruity-smelling breath.

Invega Trinza (paliperidone) can cause sleepiness, dizziness, difficulties keeping your balance, and drops in blood pressure when you sit up or stand too quickly. This can result in fainting and falling. Sit up or stand up slowly, especially during the first few days after you start Invega Trinza (paliperidone) or when your provider raises your dose. Your risk of falls is higher if you have heart problems or if you don't have enough fluids in your body. Talk to your healthcare provider if you continue to experience dizziness while taking Invega Trinza (paliperidone).

Invega Trinza (paliperidone) can lower the amount of white blood cells in your body and put you at higher risk for serious infection. You might need to get lab work done regularly to make sure your white blood cell count is healthy. If the levels are too low, your provider might stop your medication. Talk to your provider right away if you experience symptoms of an infection, including fever, weakness, or sore throat, while taking Invega Trinza (paliperidone).

Invega Trinza (paliperidone) can cause prolactin levels in the blood to go up. High prolactin levels can lead to fertility problems, enlarged male breasts, sexual dysfunction, absent or irregular menstrual periods, and weak bones. Your provider might recommend regular blood tests for you to make sure your prolactin levels are within normal range.

Invega Trinza (paliperidone) can cause extreme sleepiness and lower your ability to think, react, and focus. Your risk is higher if you're also taking other medications that can cause drowsiness, such as benzodiazepines, muscle relaxants, and sleep medications. Make sure you know how this medication affects you before driving a car or doing activities that require your concentration. Talk to your healthcare provider right away if you feel too sleepy from Invega Trinza (paliperidone).

Invega Trinza (paliperidone) can potentially cause seizures. Before starting this medication, let your provider know if you have a history of seizures or have a medical condition that puts you at risk for getting seizures.