The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Abnormal liver labs (up to 63%)
- Lower blood cell counts (up to 52%)
- Lower blood sodium levels (46%)
- Higher blood sugar (39%)
- Lower blood calcium levels (34%)
- Higher blood potassium levels (28%)
- Abnormal kidney labs (21%)
- Rash (32%)
- Diarrhea (27%)
- Fatigue (26%)
- Itching (23%)
- Muscle, bone, or joint pain (22%)
Less Common Side Effects
- Nausea
- Low appetite
- Stomach pain
- Fever
- Low thyroid hormone levels
- Trouble sleeping
Please note: Side effects listed are from studies in people with liver cancer who received treatment with Imjudo (tremelimumab) along with Imfinzi (durvalumab).
Imjudo serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Immune-related adverse events: trouble breathing, cough, diarrhea, mucus or blood in the stool, stomach pain or cramps, rash
- Infusion-related reactions: shortness of breath, itching, chills, flushing, upset stomach, or chest discomfort
Source: DailyMed
The following Imjudo side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Dry cough, shortness of breath or trouble breathing
- Eye pain, redness, irritation, or discharge with blurry or decreased vision
- Heart muscle inflammation—unusual weakness or fatigue, shortness of breath, chest pain, fast or irregular heartbeat, dizziness, swelling of the ankles, feet, or hands
- Hormone gland problems—headache, sensitivity to light, unusual weakness or fatigue, dizziness, fast or irregular heartbeat, increased sensitivity to cold or heat, excessive sweating, constipation, hair loss, increased thirst or amount of urine, tremors or shaking, irritability
- Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
- Kidney injury (glomerulonephritis)—decrease in the amount of urine, red or dark brown urine, foamy or bubbly urine, swelling of the ankles, hands, or feet
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Pancreatitis—severe stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting
- Rash, fever, and swollen lymph nodes
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Stomach pain that is severe, does not go away, or gets worse
- Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Bone, joint, or muscle pain
- Diarrhea
- Fatigue
- Loss of appetite
- Nausea
- Skin rash
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