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MIRDAMETINIB treats neurofibromatosis, a condition that causes tumors to grow along the nerves. It works by blocking a protein that causes tumor cells to grow and multiply. Compare kinase inhibitors.

Prescription Settings

Specialty Drug: Specialty drugs are often expensive and may need to be filled through specialty pharmacies. Learn More

What is Gomekli?

What should I tell my doctor?

They need to know if you have any of these conditions:

Heart disease
Vision problems
An unusual or allergic reaction to mirdametinib, other medications, foods, dyes, or preservatives
If you or your partner are pregnant or trying to get pregnant
Breastfeeding

How should I use this drug?

Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. You can take it with or without food. If it upsets your stomach, take it with food. Your care team may change your dose or tell you to stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.

This medication is taken in cycles. There will be days you do not take it. Talk to your care team if you have questions about when to take your medication. It is very important to follow the exact schedule. Taking it more often than directed can cause serious side effects.

Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 2 years for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.

If you vomit after taking your dose, do not take another dose. Take your next dose at your usual scheduled time.

Where should I store this drug?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or expired:

Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix it with cat litter, dirt, coffee grounds, or another unwanted substance. Seal the mixture in a bag or container. Put it in the trash.