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Flurbiprofen

Flurbiprofen Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on December 16, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Stomach pain
  • Upset stomach
  • Nausea
  • Diarrhea
  • Constipation
  • Headache
  • Swelling

Less Common Side Effects

Flurbiprofen serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Stomach bleeding: feeling faint, vomiting blood, bloody or dark stools, severe stomach pain or discomfort
  • Heart attack: chest pain or tightness; pain that spreads to your shoulder, arm, neck, or jaw
  • Stroke: difficulty breathing, weakness in one part of your body or face, slurred speech
  • Heart failure: difficulty breathing, swelling, fast heartbeat
  • Liver problems: swelling of your stomach, yellowing of your skin or the whites of your eyes, dark or brown urine, confusion
  • Kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
  • Serious allergic reaction or skin reaction: hives, rash, blisters, skin reddening, blisters, swelling of the lips or tongue, difficulty breathing
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Source: DailyMed

The following Flurbiprofen side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Abdominal or stomach pain

bladder pain

bloody or black, tarry stools

bloody or cloudy urine

constipation

difficult, burning, or painful urination

frequent urge to urinate

lower back or side pain

rash

severe stomach pain

swelling

vomiting of blood or material that looks like coffee grounds

Rare

Back or leg pains

bleeding gums

blistering, peeling, or loosening of the skin

bloody diarrhea

bloody nose

blurred vision

burning feeling in the chest or stomach

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain

chills

clay-colored stools

cough

cracks in the skin

dark urine

decreased urine output

difficulty breathing

difficulty swallowing

dilated neck veins

dizziness

extreme fatigue

fast heartbeat

feeling faint, dizzy, or lightheaded

feeling of warmth or heat

fever with or without chills

flushing or redness of the skin, especially on the face and neck

general feeling of tiredness or weakness

greatly decreased frequency of urination

headache

high fever

hives or itching

hoarseness

increased blood pressure

increased sensitivity of the skin to sunlight

increased thirst

indigestion

irregular breathing

irregular heartbeat

joint pain, stiffness, or swelling

large, flat, blue, or purplish patches in the skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

loss of heat from the body

muscle pain

nausea

nervousness

noisy breathing

nosebleeds

pale skin

pinpoint red or purple spots on the skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes

red, swollen skin

redness or other discoloration of the skin

redness, swelling, or soreness of the tongue

scaly skin

severe or continuing stomach pain

severe sunburn

shakiness and unsteady walk

skin rash, encrusted, scaly and oozing

slow or fast heartbeat

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stomach bloating or cramping

stomach upset

sweating

swelling of the face, fingers, feet, or lower legs

swelling or inflammation of the mouth

swollen or painful glands

tenderness in the stomach area

tightness in the chest

troubled breathing

unpleasant breath odor

unsteadiness, trembling, or other problems with muscle control or coordination

unusual bleeding or bruising

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting

weight gain

weight loss

yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptom of overdose

Change in consciousness

fast or slow, or shallow breathing

heartburn

loss of consciousness

pain or discomfort in the chest, upper stomach, or throat

pale or blue lips, fingernails, or skin

unusual drowsiness, dullness, or feeling of sluggishness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Acid or sour stomach

belching

changes in vision

continuing ringing or buzzing or other unexplained noise in the ear

diarrhea

discouragement

excess air or gas in the stomach or intestines

fear

feeling of constant movement of self or surroundings

feeling sad or empty

full feeling

general feeling of discomfort or illness

hearing loss

irritability

lack of appetite

lack or loss of strength

lightheadedness

loss of interest or pleasure

loss of memory

passing gas

problems with memory

runny nose

sensation of spinning

sleepiness

sneezing

stomach discomfort

stuffy nose

tremor

trouble concentrating

trouble sleeping

Rare

Burning, dry, or itching eyes

confusion

discharge or excessive tearing

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

transient, mild, pleasant aromatic odor

twitching

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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