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Fluconazole Coupon - Fluconazole 150mg tablet

fluconazole

Generic Diflucan
Used for Yeast Infection, Fungal Infection, Thrush
Used for Yeast Infection, Fungal Infection, Thrush

Fluconazole (Diflucan) is an azole antifungal. It's used to treat different types of Candida infections, such as vaginal yeast infections and oral thrush. It can also treat a serious brain infection called cryptococcal meningitis. Oral fluconazole (Diflucan) is available as a tablet and suspension. It's taken by mouth as a one-time dose for vaginal yeast infections; it's typically taken once daily for other types of infections. Fluconazole (Diflucan) is generally well-tolerated, but some people can experience side effects like headache, nausea, and stomach pain. Fluconazole (Diflucan) can raise the risk of liver problems, so you're recommend to avoiding drinking alcohol while taking this medication.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Kristianne Hannemann, PharmD
Last reviewed on May 15, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
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What is Fluconazole (Diflucan)?

02:25
Featuring Nabila Ismail, PharmD
Reviewed by Connie Zheng, PharmD, Mera Goodman, MD, FAAP | July 31, 2024

What is Fluconazole (Diflucan) used for?

How Fluconazole (Diflucan) works

Fluconazole (Diflucan) is an azole antifungal medication that works by stopping the fungus from being able to make a protective covering. This causes the fungus to not grow or survive.

Drug Facts

Common BrandsDiflucan
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Fluconazole (Diflucan) essentials

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What are the side effects of Fluconazole (Diflucan)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Single dose for vaginal yeast infection:
  • Headache (13%)
  • Nausea (7%)
  • Stomach pain (6%)
  • Diarrhea (3%)
Multiple doses for other infections:
  • Nausea (4%)
  • Headache (2%)
  • Skin rash (2%)
  • Vomiting (2%)
  • Stomach pain (2%)
  • Diarrhea (2%)

Other Side Effects

  • Dizziness
  • Changes to taste
  • Skin rash

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Liver damage: nausea, vomiting, feeling tired, stomach pain, yellowing of your skin or whites of your eye (jaundice), dark-colored urine, pale-colored stool
  • Serious allergic and skin reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing, skin reddening, skin scaling, skin itching
  • Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded

Source: DailyMed

More on Fluconazole (Diflucan) side effects

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The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Chills

clay-colored stools

cough

dark urine

diarrhea

difficulty with swallowing

dizziness

fast heartbeat

fever

general feeling of tiredness or weakness

headache

hives, itching, or skin rash

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

light-colored stools

loss of appetite

nausea

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

stomach pain, continuing

tightness in the chest

unpleasant breath odor

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting

vomiting of blood

yellow eyes and skin

Incidence not known

Black, tarry stools

blistering, peeling, or loosening of the skin

chest pain or discomfort

decreased urine

dry mouth

fainting

hoarseness

increased thirst

irregular or slow heart rate

joint or muscle pain

loss of bladder control

lower back or side pain

mood changes

muscle pain or cramps

muscle spasm or jerking of the arms and legs

numbness or tingling in the hands, feet, or lips

painful or difficult urination

pale skin

red skin lesions, often with a purple center

red, irritated eyes

seizures

sore throat

sores, ulcers, or white spots in the mouth or on the lips

sudden loss of consciousness

swollen glands

unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Fearfulness, suspiciousness, or other mental changes

seeing, hearing, or feeling things that are not there

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Belching

change in taste or bad, unusual, or unpleasant (after) taste

heartburn

indigestion

stomach discomfort or upset

Incidence not known

Hair loss or thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Fluconazole (Diflucan)

thumbs-up

Pros

Taken once daily for most infections

Considered acceptable to take while breastfeeding

Oral liquid comes flavored for better taste

Available as a lower-cost generic

thumbs-down

Cons

Interacts with many medications

Not recommended during pregnancy due to the potential risk of harm to babies

Rare risk of liver problems

pharmacist-tips

Pharmacist tips for Fluconazole (Diflucan)

pharmacist

  • You can take fluconazole (Diflucan) with or without food. But nausea and stomach pain are common, so taking it with food can help ease or prevent these from happening.

    • Make sure to finish your entire treatment course. Don't stop taking fluconazole (Diflucan) early unless your prescriber specifically told you to do so. Stopping fluconazole (Diflucan) too soon can cause your infection to come back and become more difficult to treat.

      • If you're taking fluconazole (Diflucan) to treat a vaginal yeast infection, avoid having sex until your infection is completely better. Having sex before your infection is cleared up can be painful and make symptoms, like burning and itching, worse. There's also a risk to pass the infection to your partner.

        • Although rare, fluconazole (Diflucan) can cause dizziness and seizures. Be careful while driving or operating machinery, especially if you have a history of seizures or other nervous system problems.

          • Contact your prescriber if you develop other symptoms of an illness or if your symptoms become worse. This could be a sign that you're infected with a virus or bacteria instead of a fungus. If so, you'll need to a different medication than fluconazole (Diflucan) because it's only used to treat certain fungal infections.

            • If you're able to become pregnant, you're recommended to use effective birth control during fluconazole (Diflucan) treatment and for at least 1 week after your last dose. There's a chance that fluconazole (Diflucan) can cause birth defects.

              More tips for fluconazole (Diflucan) oral suspension

              • Shake the oral suspension each time before you measure out and take your dose.

                • Only use the measuring device provided at the pharmacy. Don't use household spoons to measure your dose since this could cause you to take the wrong amount.

                  • Store fluconazole (Diflucan) at room temperature. The suspension is good for 2 weeks from when you receive it from the pharmacy. Throw the medication away after 2 weeks, even if there's still some left over.

                    More on Fluconazole (Diflucan) tips

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                    faqs

                    Frequently asked questions about Fluconazole (Diflucan)

                    Is fluconazole (Diflucan) an antibiotic?
                    No, fluconazole (Diflucan) is an antifungal, meaning it treats infections caused by fungus. Antibiotics, however, are used to treat infections caused by bacteria.
                    How long does fluconazole (Diflucan) take to work?
                    How long it takes for fluconazole (Diflucan) to work depends on different factors, such as the type of infection you're taking it to treat and how serious it is. For example, if you're taking fluconazole (Diflucan) for a vaginal yeast infection, your symptoms should improve within 1-3 days. But if you're taking fluconazole (Diflucan) for oral thrush, your might need to continue treatment for several days before you notice any improvement. Continue taking fluconazole (Diflucan) for the amount of time your prescriber recommended, even if you start to feel better. Stopping treatment too early can cause your infection to come back or be harder to treat.
                    How often can you take fluconazole (Diflucan) for a vaginal yeast infection?
                    The typical dose for treating a vaginal yeast infection is fluconazole (Diflucan) 150 mg by mouth once as a single dose. If your symptoms don't go away within 3 days after the dose, your HCP will instruct you to take a dose of fluconazole (Diflucan) every 3 days for a total of 3 doses. But if you have vaginal yeast infections more than 3 times within a year, your HCP might ask you to take fluconazole (Diflucan) daily for a longer period of time to control the infection. Ask your healthcare team if you've more questions about how long you should take this medication.
                    Does fluconazole (Diflucan) treat bacterial vaginosis (BV)?
                    No, fluconazole (Diflucan) doesn't treat bacterial vaginosis (BV). BV is a bacterial infection, so it's treated with antibiotics like metronidazole (Flagyl) or clindamycin (Clindesse) vaginal cream. Fluconazole (Diflucan) is an antifungal, so it doesn't work for bacterial infections, just fungal infections. Symptoms of a vaginal yeast infection and BV are similar (e.g., itching, burning, irritation), so make sure to check with your gynecologist if you have these symptoms. They'll make sure you receive the most appropriate treatment for your condition.
                    Can you drink alcohol while taking fluconazole (Diflucan)?
                    You should avoid drinking alcohol until you've finished your course of fluconazole (Diflucan). Drinking alcohol can weaken your immune system and make it harder to recover from an infection. Additionally, drinking alcohol while taking fluconazole (Diflucan) raises your risk for stomach-related side effects (e.g., nausea, vomiting, diarrhea) as well as the risk for liver problems. If avoiding alcohol isn't possible for you, talk to your prescriber about what's a reasonably safe amount of alcohol to drink while taking fluconazole (Diflucan).
                    Can you take fluconazole (Diflucan) while pregnant?
                    Typically, HCPs will avoid prescribing fluconazole (Diflucan) for people who are pregnant unless they have a serious infection that can't be treated with a safer option. Research shows taking higher doses of fluconazole (Diflucan) regularly during pregnancy can cause harm to unborn babies. While the same risk isn't linked to the single 150 mg dose of fluconazole (Diflucan) for vaginal yeast infections, it's also not recommended during pregnancy because of potential harm. Talk with your healthcare team if you have questions about fluconazole (Diflucan) and pregnancy.
                    How long do fluconazole (Diflucan) side effects last?
                    How long the side effects of fluconazole (Diflucan) last depends on what symptoms you're experiencing and whether they can be managed with lifestyle changes or other medications. For example, one of the more common side effects of fluconazole (Diflucan) is headache, which typically goes away on its own. But in the meantime, you can ease headache by drinking enough water or taking an over-the-counter pain medication that's safe for you. Another example is that taking fluconazole (Diflucan) can raise the risk for liver problems. This side effect is rare and typically don't lead to symptoms, but your HCP might ask you to avoid drinking alcohol while you're taking fluconazole (Diflucan) to minimize the risk of serious liver damage. Talk to your healthcare team if you're concerned with certain side effects of fluconazole (Diflucan).
                    How long does fluconazole (Diflucan) stay in your system?
                    It takes about 6 days for most of fluconazole (Diflucan) to leave your body after a dose. This timeframe is estimated based on the half-life of fluconazole (Diflucan). But if you have kidney problems, it can take up to 20 days for the body to remove fluconazole (Diflucan). Because this medication can stay in the body for a long time and has the potential to cause birth defects, anyone who is able to become pregnant should use birth control until at least a week after their last dose. Talk with your healthcare team if you have specific concerns about how long this medication might stay in your body.
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                    warings-icon

                    What are the risks and warnings for Fluconazole (Diflucan)?

                    Fluconazole (Diflucan) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                    risk-warning

                    Liver damage

                    • Risk factors: Liver problems | Excessive alcohol use

                      Although rare, people who took fluconazole (Diflucan) have developed liver problems. Because of this risk, your prescriber might order blood tests before you start and during treatment to check your liver function tests to make sure your liver is healthy. Also, it's recommended to limit or avoid alcohol because it can also cause liver damage. Get medical attention right away if you notice yellowing of your skin or the whites of your eyes; stool changes; dark or brown urine; swelling of your stomach; stomach pain; or confusion. Your prescriber might ask you to stop taking fluconazole (Diflucan) in order to prevent further liver damage.

                      risk-warning

                      Allergic reaction

                      Severe allergic reactions to fluconazole (Diflucan) are possible, including life-threatening reactions like facial swelling, hives, and anaphylaxis (e.g., closing of the throat). If you notice difficulty breathing; a choking sensation; dizziness; fast heartbeat; nausea; or swelling around your eyes, lips, or tongue after taking fluconazole (Diflucan), get medical attention right away.

                      risk-warning

                      Severe skin reaction

                      Very rarely, people have developed a serious, potentially life-threatening skin reaction called exfoliative dermatitis after starting fluconazole (Diflucan). This serious rash can cause itchiness, redness all over your body, and scaly and peeling skin. Get medical help right away if you notice a new or severe rash with fever, skin redness, or unexplained blisters.

                      risk-warning

                      Harm to unborn babies

                      It's generally recommended to avoid using fluconazole (Diflucan) while pregnant unless there's a clear need for the medication. While there haven't been a lot of studies about the safety of fluconazole (Diflucan) during pregnancy, the studies that are available suggest there's a small chance it can cause harm to babies. Examples include problems in the heart, head, face, and bones. If you're taking 400 mg to 800 mg of fluconazole (Diflucan) per day, it's recommended to use birth control during treatment and for 1 week after your last dose. If you become pregnant while you're taking fluconazole (Diflucan), stop taking the medication right away and talk to your prescriber about the risks and benefits of continuing to use the medication.

                      dosage

                      Fluconazole (Diflucan) dosage forms

                      The average cost for 2 tablets of 150mg of Fluconazole (Diflucan) is $10.42 with a free GoodRx coupon. This is 50.63% off the average retail price of $21.11.
                      bottle of oral suspension
                      Bottle of oral suspension
                      DosageQuantityPrice as low asPrice per unit
                      35ml of 10mg/ml1 bottle$17.83$17.83
                      35ml of 40mg/ml1 bottle$29.06$29.06
                      tablet
                      Tablet
                      DosageQuantityPrice as low asPrice per unit
                      50mg60 tablets$19.86$0.33
                      100mg7 tablets$7.14$1.02
                      150mg2 tablets$10.42$5.21
                      200mg60 tablets$35.84$0.60

                      Typical dosing for Fluconazole (Diflucan)

                      Your healthcare provider will determine your dose of fluconazole (Diflucan) and length of treatment based on different factors, such as the type of infection you have and severe it is.

                      Adults:

                      • Vaginal yeast infection: The typical dose is 150 mg by mouth as a single dose.

                      • Mouth, throat, or esophagus infections: The typical dose is 200 mg by mouth on the first day, followed by 100 mg once daily. Treatment typically lasts at least 2 weeks.

                      • Blood, lung, or other whole-body infection: The optimal dose hasn't been determined. Doses up to 400 mg daily have been prescribed. Ask your HCP for more information.

                      • UTI and peritonitis: The typical dose ranges from 50 mg to 200 mg by mouth once daily.

                      • Prevention of fungal infection: The typical dose is 400 mg by mouth once daily.

                      • Cryptococcal meningitis: The typical dose is 400 mg by mouth on the first day, followed by 200 mg once daily. Most people with this condition will take fluconazole (Diflucan) for several months.

                      Children:
                      Your child's pediatrician will determine the dose based on your child's body weight and age.

                      • Mouth, throat, or esophagus infections: The typical dose is 6 mg/kg of body weight by mouth on the first day, then 3 mg/kg by mouth once per day. Treatment typically lasts at least 2 weeks.

                      • Whole-body infection: The typical dose is 25 mg/kg by mouth on the first day, then 9 mg/kg to 12 mg/kg by mouth once daily.

                      • Cryptococcal meningitis: The typical dose is 12 mg/kg by mouth on the first day, then 6 mg/kg by mouth once daily. Most children with this condition will take fluconazole (Diflucan) for several months.

                      Your dose might be different if you have kidney problems.

                      Fluconazole (Diflucan) is also available as an intravenous (IV) injection that's given by a healthcare professional.

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                      interactions

                      Interactions between Fluconazole (Diflucan) and other drugs

                      Fluconazole (Diflucan) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Fluconazole (Diflucan). Please note that only the generic name of each medication is listed below.

                      More on Fluconazole (Diflucan) interactions

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                      Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                      Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                      contraindications-icon

                      Fluconazole (Diflucan) contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Fluconazole (Diflucan) will not be safe for you to take.
                      alternatives

                      What are alternatives to Fluconazole (Diflucan)?

                      There are a number of medications that your doctor can prescribe in place of Fluconazole (Diflucan). Compare a few possible alternatives below.
                      Fluconazole (Diflucan)
                      Used for:
                      $7.14 Lowest GoodRx priceView Prices
                      Voriconazole (Vfend)
                      Used for:
                      $76.70 Lowest GoodRx priceView Prices
                      Posaconazole (Noxafil)
                      Used for:

                      • Prevention of serious fungal infections caused by Candida and Aspergillus

                      • Treatment of serious Aspergillus infection - tablets only

                      • Treatment of oral thrush of the mouth and throat - liquid suspension only

                      $249.98 Lowest GoodRx priceView Prices
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                      Fluconazole (Diflucan) images

                      Pink Oblong 10 And C - Fluconazole 150mg Tablet
                      This medicine is Pink, Oblong Tablet Imprinted With "10" And "C".Pink Oblong 10 And C - Fluconazole 150mg Tablet
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                      References

                      Best studies we found

                      American Thoracic Society. (2019). Candidemia (Blood Infection) and Other Candida Infections.

                      Aurobindo Pharma Limited. (2023). Fluconazole [package insert]. DailyMed.

                      Austad, S. S., et al. (2022). Exfoliative dermatitis. StatPearls.

                      View All References (18)

                      Blot, S.I., et al. (2007). Candida peritonitis. Current Opinion in Critical Care.

                      Centers for Disease Control and Prevention. (2021). Vulvovaginal candidiasis.

                      Centers for Disease Control and Prevention. (2022). Bacterial vaginosis (BV): Fact sheet.

                      Cousin, L. (2003). Dosing guidelines for fluconazole in patients with renal failure. Nephrology Dialysis Transplantation.

                      Drugs and Lactation Database (LactMed®). (2018). Fluconazole.

                      Fisher, J.F., et al. (2011). Candida urinary tract infection: pathogenesis. Clinical Infectious Diseases.

                      Heritage Pharmaceuticals. (2022). Nystatin tablet [package insert]. DailyMed.

                      Herrick, E.J., et al. (2024). Antifungal Ergosterol Synthesis Inhibitors. Statpearls.

                      Hikma Pharmaceuticals USA. (2021). Fluconazole [package insert]. DailyMed.

                      Marco, A., et al. (2023). Cryptococcal Meningitis. Statpearls.

                      MedlinePlus. (2022). Bone marrow transplant.

                      MotherToBaby. (2023). Fluconazole (Diflucan®).

                      Meena, D.S. (2022). Candida Pneumonia: An Innocent Bystander or a Silent Killer? Medical Principles and Practice.

                      Nivagen Pharmaceuticals. (2022). Nystatin suspension [package insert]. DailyMed.

                      Office of the Assistant Secretary of Health. (2021). Vaginal yeast infections.

                      Pappas, P. G., et al. (2015). Clinical practice guidelines for the management of candidiases: 2016 update by the Infectious Diseases Society of America. Clinical Infectious Diseases.

                      Roerig. (2024). Diflucan [package insert]. DailyMed.

                      U.S. Food and Drug Administration. (2017). FDA drug safety communication: Use of long-term, high-dose Diflucan (fluconazole) during pregnancy may be associated with birth defects in infants.

                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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