The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Breast pain (8-9%)
- Headache (6%)
- Stomach pain (5-7%)
- Swelling anywhere in the body (4-5%)
Less Common Side Effects
- Changes in vaginal bleeding (e.g., breakthrough bleeding, spotting)
- Vaginal yeast infection
- Breast enlargement
- Nausea
- Vomiting
- Mood changes
- Trouble sleeping
- Weight changes
- Rash
- Itching
Femhrt serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Blood clots: trouble breathing, leg pain or swelling, skin that's warm to the touch
- Heart attack: chest pain, arm pain, shortness of breath, cold sweats, lightheadedness
- Stroke: sudden weakness on one side of your body, drooping face, changes in your speech or vision, confusion, headache
- Uterine or ovarian cancer: unusual vaginal bleeding, pelvic pain
- Breast cancer: swelling, redness, or irritation of breast, lump in breast or armpit
- Abnormal changes in calcium levels: tiredness, muscle weakness, muscle spasms or twitching, nausea, vomiting, constipation, numbness and tingling in your fingers, toes, or around your mouth
Source: DailyMed
The following Femhrt side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
- Breast tissue changes, new lumps, redness, pain, or discharge from the nipple
- Gallbladder problems—severe stomach pain, nausea, vomiting, fever
- Increase in blood pressure
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- New or worsening migraines or headaches
- Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
- Unusual vaginal discharge, itching, or odor
- Vaginal bleeding after menopause, pelvic pain
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Breast pain or tenderness
- Headache
- Swelling of the ankles, hands, or feet
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