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Excedrin Migraine

Excedrin Migraine Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on August 3, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Excedrin Migraine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: trouble breathing, blisters, hives, swelling of your tongue or lips
  • Serious bleeding: feeling faint or lightheaded, dizziness, vomiting blood, bloody or dark-colored stools, severe stomach pain
  • Liver problems: dark urine, feeling tired, upset stomach or stomach pain, yellowing of skin or eyes
  • Kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
  • Severe dehydration: dry mouth, not urinating as much, lightheadedness, dizziness
When do Excedrin Migraine possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Stomach upset
Trouble sleeping
Nervousness or restlessness
Risk for stomach bleeding or ulcer
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Excedrin Migraine side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
  • Hearing loss, ringing in ears
  • Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Rash, fever, and swollen lymph nodes
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth
  • Round red or dark patches on the skin that may itch, burn, and blister

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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