The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Sleepiness
- Restlessness
- Dizziness
- Dry mouth
Less Common Side Effects
- Headache
- Trouble urinating
Acetaminophen/Chlorpheniramine/Dextromethorphan/Phenylephrine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions: rash; hives; difficulty breathing; swelling of face, lips, tongue, or throat
- Serious skin reaction: skin reddening, skin peeling, blisters, rash
- Liver damage: severe stomach pain, yellowing of skin or eyes, nausea, vomiting, loss of appetite
- Excessive sleepiness or dizziness
- Serotonin syndrome: fast heart rate, sweating, muscle stiffness or spasms, high fever, confusion
- Accidentally taking too much medication: seizures, heart rhythm problems, hallucinations, confusion, flushed skin, skin that's warm to the touch, vision changes, severe stomach pain, yellowing of skin or eyes
When do Acetaminophen/Chlorpheniramine/Dextromethorphan/Phenylephrine possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Sleepiness
Dizziness
Dry mouth
Restlessness
Source: DailyMed
The following Acetaminophen/Chlorpheniramine/Dextromethorphan/Phenylephrine side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Heart palpitations—rapid, pounding, or irregular heartbeat
- Increase in blood pressure
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
- Trouble passing urine
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Anxiety, nervousness
- Confusion
- Constipation
- Dizziness
- Drowsiness
- Dry mouth
- Fatigue
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