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Duraflu

Duraflu Side Effects

Ally Tsai, PharmDKristianne Hannemann, PharmD
Reviewed by Ally Tsai, PharmD, Kristianne Hannemann, PharmD
Last reviewed on May 23, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Possible pseudoephedrine side effects:

  • Feeling anxious
  • Confusion
  • Tremor
  • Dry mouth
  • Indigestion
  • Excessive sweating

Less Common Side Effects

Possible acetaminophen side effects:

  • Nausea
  • Headache

Possible dextromethorphan side effects:

  • Belly discomfort
  • Vomiting
  • Drowsiness

Possible guaifenesin side effects:

  • Diarrhea
  • Dizziness

Duraflu serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Liver damage: nausea, vomiting, loss of appetite, severe stomach pain, yellowing of the skin or whites of the eyes
  • Serotonin syndrome: fast heart rate, sweating, muscle stiffness or spasms, high fever, confusion
  • Severe skin reaction: skin reddening, blisters, rash

Source: DailyMed

The following Duraflu side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Heart palpitations—rapid, pounding, or irregular heartbeat
  • Increase in blood pressure
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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