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Etoposide

Etoposide Side Effects

Connie Zheng, PharmDDaisy Chau, PharmD
Reviewed by Connie Zheng, PharmD, Daisy Chau, PharmD
Last reviewed on October 31, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low white blood cell count (up to 91%)
  • Hair loss (up to 66%)
  • Low platelet count (up to 41%)
  • Nausea and vomiting (up to 43%)
  • Low red blood cell count (up to 33%)

Please note: These side effects were reported by people taking either etoposide alone, either by mouth or as an infusion. The side effects you experience might differ depending on what other anticancer medications you're taking.

Less Common Side Effects

  • Low appetite
  • Diarrhea
  • Mouth sores
  • Stomach pain
  • Tingling or numbness in the hands and feet

Etoposide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious infections: headache, fevers, chills, body aches, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
  • Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stools

Source: DailyMed

The following Etoposide side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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