The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Multiple sclerosis
- Nausea (up to 76%)
- Hair thinning (up to 61%)
- Changes to menstrual bleeding (up to 61%)
- Upper respiratory tract infection (up to 53%)
- Urinary tract infection (up to 32%)
- Diarrhea (up to 25%)
Prostate cancer
- Changes in blood cell counts (up to 87%)
- Nausea (up to 61%)
- Changes in alkaline phosphatase (up to 37%)
- Tiredness (up to 34%)
- Higher blood sugar levels (up to 31%)
- Swelling (up to 30%)
- Hair thinning (up to 29%)
- Poor appetite (up to 25%)
Leukemia
- Fever (up to 78%)
- Nausea or vomiting (up to 72%)
- Diarrhea (up to 47%)
- Hair thinning (up to 37%)
- Sepsis (up to 34%)
- Sores or inflammation inside the mouth or gut (up to 29%)
Less Common Side Effects
- Weakness
- Headache
- Irregular heartbeat
- Constipation
- Stomach pain
- Stomach bleeds
- Bleeding under the skin (small red or purple dots; bruise)
- Nail bed changes
- Cough
- Shortness of breath
- Throat infection
- Fungal infections
- Changes in weight
Please note: Side effects listed might not be from [[EDITOR|DRUG_DISPLAY_NAME]] alone. Some people who took [[EDITOR|DRUG_DISPLAY_NAME]] in clinical trials also took other anticancer medications.
Mitoxantrone serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Low blood cell counts (myelosuppression): feeling tired, getting infections more often, bruising and bleeding easily
- Heart problems: shortness of breath, swelling of your ankles or feet, sudden weight gain, fast heartbeat, pounding in your chest
Source: DailyMed
The following Mitoxantrone side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Black, tarry stools
bladder pain
bloody or cloudy urine
cough or shortness of breath
difficult, burning, or painful urination
dizziness
fainting
fast, slow, or irregular heartbeat
frequent urge to urinate
lower back or side pain
pale skin
stomach pain
swelling or inflammation of the mouth
troubled breathing with exertion
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
Less common
Blood in the urine or stools
decrease in urination
fever or chills
pinpoint red spots on the skin
seizures
sore, red eyes
swelling of the feet and lower legs
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Absent, missed, or irregular menstrual periods
back pain
body aches or pains
congestion
dryness or soreness of the throat
headache
longer or heavier menstrual periods
nausea or vomiting
oral bleeding
pain or tenderness around the eyes and cheekbones
stopping of menstrual bleeding
tender, swollen glands in the neck
thinning of the hair
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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