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Ethambutol

Ethambutol Side Effects

Allison Gourley, PharmDCydnee Ng, PharmD
Reviewed by Allison Gourley, PharmD, Cydnee Ng, PharmD
Last reviewed on February 25, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Blurry vision
  • Nausea or vomiting
  • Upset stomach
  • Stomach pain
  • Fever
  • Feeling unwell
  • Headache
  • Dizziness

Less Common Side Effects

  • Numbness and tingling of the arm or leg
  • Confusion
  • Hallucinations (seeing or hearing things that aren't there)
  • Gout attack
  • Low blood cell counts
  • Abnormal lung scan

Ethambutol serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Vision problems: blurry vision, color blindness, blind spots in your vision
  • Liver injury: fatigue, nausea, loss of appetite, yellowing of the skin and eyes, dark urine, pale stool
  • Allergic reaction: skin rash, redness, scaling
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Source: DailyMed

The following Ethambutol side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Chills

pain and swelling of joints, especially big toe, ankle, or knee

tense, hot skin over affected joints

Rare

Blurred vision, eye pain, red-green color blindness, or any loss of vision (more common with high doses)

fever

joint pain

numbness, tingling, burning pain, or weakness in hands or feet

skin rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abdominal pain

confusion

headache

loss of appetite

nausea and vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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