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Cycloserine

Cycloserine Side Effects

Aileen Chu, PharmD, BCPSCydnee Ng, PharmD
Reviewed by Aileen Chu, PharmD, BCPS, Cydnee Ng, PharmD
Last reviewed on December 5, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Side effects are more likely to happen at doses greater than 500 mg per day.

  • Sleepiness
  • Headache
  • Tremor (shakiness)
  • Trouble speaking or slurred speech
  • Feeling like your surroundings are spinning (vertigo)
  • Confusion
  • Memory problems
  • Changes in mood, thoughts, or behaviors

Less Common Side Effects

  • Skin rash

Cycloserine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Seizures
  • Heart failure: shortness of breath, swelling in the stomach or legs, sudden weight gain, tiredness, dizziness
  • Allergic reaction: rash, hives, trouble breathing, swelling of the face

Source: DailyMed

The following Cycloserine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Anxiety

confusion

dizziness

drowsiness

increased irritability

increased restlessness

mental depression

muscle twitching or trembling

nervousness

nightmares

other mood or mental changes

speech problems

thoughts of suicide

Less common

Convulsions (seizures)

numbness, tingling, burning pain, or weakness in the hands or feet

skin rash

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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