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Estrogel (estradiol) is used for symptoms of menopause like hot flashes, night sweats, and mood changes. It is slightly more popular than comparable drugs. There are currently no generic alternatives to Estrogel.
GoodRx has partnered with InsideRx and Ascend Therapeutics to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Estrogel is covered by most Medicare and insurance plans.
Get Estradiol for as low as $169.38, which is 74% off the average retail price of $647.63 for the most common version, by using a GoodRx coupon.
You can save more on select medications with GoodRx Companion. See which medications are eligible.
| Dosage | Quantity | Retail price | GoodRx price |
|---|---|---|---|
| 50g of 0.06% | 3 pumps | $439.44 | $169.38 |
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GoodRx coupon prices last updated on 10/15/26.
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