Esomep-Ezs is part of the Proton Pump Inhibitors class and treats Gastric Ulcer and GERD. Proton pump inhibitors are used to treat GERD, gastric ulcers, duodenal ulcers, and heartburn. They work by healing the esophagus and by decreasing the amount of stomach acid. Esomep-Ezs is only available as a generic drug.