The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Dry mouth (up to 35%)
- Constipation (up to 21%)
- Urinary tract infection (5%)
Less Common Side Effects
- Indigestion
- Stomach pain
- Nausea
- Diarrhea
- Dizziness
- Weakness
- Headache
- Dry skin
- Dry eyes
- Blurry vision
- Flu-like symptoms
- Swelling (edema)
- Weight gain
Darifenacin ER serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Angioedema (severe swelling): swelling of the face, lips, tongue, or throat; trouble breathing
Source: DailyMed
More on Darifenacin ER side effects

The following Darifenacin ER side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Bladder pain
bloody or cloudy urine
difficult, burning, or painful urination
frequent urge to urinate
lower back or side pain
Incidence not known
Decrease in the frequency of urination
decrease in the urine volume
difficulty in passing urine
dribbling or painful urination
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Changes in vision
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Acid or sour stomach
belching
difficulty having a bowel movement (stool)
indigestion
stomach discomfort, upset, or pain
Incidence not known
Accidental injury
bloating or swelling of the face, arms, hands, lower legs, or feet
changes in vision
chills
congestion
cough producing mucus
difficulty with breathing
difficulty with moving
dryness or soreness of the throat
general feeling of discomfort or illness
headache
hoarseness
itching of the vagina or genital area
itching skin
joint pain
loss of appetite
muscle aches and pains
muscle stiffness
nervousness
pain during sexual intercourse
pain or tenderness around the eyes and cheekbones
pounding in the ears
rash
shortness of breath or troubled breathing
slow or fast heartbeat
tender, swollen glands in the neck
thick, white vaginal discharge with no odor or with a mild odor
tightness in the chest
tingling of the hands or feet
trouble with swallowing
unusual weight gain or loss
voice changes
vomiting
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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