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Darifenacin ER

Darifenacin ER Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on February 21, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Less Common Side Effects

  • Indigestion
  • Stomach pain
  • Nausea
  • Diarrhea
  • Dizziness
  • Weakness
  • Headache
  • Dry skin
  • Dry eyes
  • Blurry vision
  • Flu-like symptoms
  • Swelling (edema)
  • Weight gain

Darifenacin ER serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Angioedema (severe swelling): swelling of the face, lips, tongue, or throat; trouble breathing
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When do Darifenacin ER possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Dry mouth
Risk of severe swelling of the face, tongue, or throat
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

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The following Darifenacin ER side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Bladder pain

bloody or cloudy urine

difficult, burning, or painful urination

frequent urge to urinate

lower back or side pain

Incidence not known

Decrease in the frequency of urination

decrease in the urine volume

difficulty in passing urine

dribbling or painful urination

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Changes in vision

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

belching

difficulty having a bowel movement (stool)

dry mouth

heartburn

indigestion

stomach discomfort, upset, or pain

Less common

Diarrhea

dizziness

dry eyes

lack or loss of strength

nausea

Incidence not known

Accidental injury

bloating or swelling of the face, arms, hands, lower legs, or feet

changes in vision

chills

congestion

cough producing mucus

difficulty with breathing

difficulty with moving

dry skin

dryness or soreness of the throat

fever

general feeling of discomfort or illness

headache

hoarseness

itching of the vagina or genital area

itching skin

joint pain

loss of appetite

muscle aches and pains

muscle stiffness

nervousness

pain during sexual intercourse

pain or tenderness around the eyes and cheekbones

pounding in the ears

rash

runny nose

shortness of breath or troubled breathing

slow or fast heartbeat

sneezing

stuffy nose

tender, swollen glands in the neck

thick, white vaginal discharge with no odor or with a mild odor

tightness in the chest

tingling of the hands or feet

trouble with swallowing

unusual weight gain or loss

voice changes

vomiting

wheezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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