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Tolterodine

Tolterodine Side Effects

Ashley Wong, PharmDKristianne Hannemann, PharmD
Reviewed by Ashley Wong, PharmD, Kristianne Hannemann, PharmD
Last reviewed on November 24, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Immediate-release tablets:

  • Dry mouth (35%)
  • Headache (7%)
  • Constipation (7%)
  • Stomach pain (5%)
  • Dizziness or feeling like you're spinning (5%)

Extended-release capsules:

  • Dry mouth (23%)
  • Headache (6%)
  • Constipation (6%)
  • Stomach pain (4%)

Less Common Side Effects

  • Tiredness
  • Dizziness
  • Blurry vision
  • Diarrhea
  • Indigestion
  • Flu-like symptoms

Tolterodine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction or angioedema (swelling): rash; hives; swelling in the face, lips, tongue, or throat; trouble breathing; wheezing
When do Tolterodine possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Dry mouth
Constipation
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Tolterodine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abnormal vision, including difficulty with adjusting to distances

bloody or cloudy urine

difficult, burning, or painful urination

frequent urge to urinate

Less common

Chest pain

chills

cough

diarrhea

fever

general feeling of discomfort or illness

headache

joint pain

loss of appetite

muscle aches and pains

nausea

pain or tenderness around the eyes and cheekbones

shivering

shortness of breath or troubled breathing

sore throat

stuffy or runny nose

sweating

tightness of the chest or wheezing

trouble with sleeping

vomiting

Incidence not known

Being forgetful

bloating or swelling of the face, arms, hands, ankles, lower legs, or feet

confusion about identity, place, and time

difficulty with swallowing

dizziness

fast, pounding, or irregular heartbeat or pulse

hives

itching

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

mood or mental changes

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rapid weight gain

seeing, hearing, or feeling things that are not there

skin rash

tingling of the hands or feet

unusual tiredness or weakness

unusual weight gain or loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal or stomach pain

constipation

drowsiness

dry eyes

dry mouth

upset stomach

Less common

Acid or sour stomach

belching

blurred vision

difficulty with moving

dizziness or lightheadedness

dry skin

fear or nervousness

feeling of constant movement of self or surroundings

heartburn

indigestion

sensation of spinning

sleepiness or unusual drowsiness

stomach discomfort

weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Ashley Wong, PharmD, is a licensed pharmacist in California. She has over 6 years of experience providing drug information.
Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

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