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Solifenacin

Solifenacin Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on October 4, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dry mouth (up to 28% in adults, 8% in children)
  • Constipation (up to 13% in adults, 3% in children)

Less Common Side Effects

Solifenacin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Angioedema (severe swelling): swelling of the face, lips, tongue, or throat; trouble breathing
  • Abnormal heart rhythm: chest pounding, fast heartbeat, irregular heartbeat, chest pain, short of breath, feeling faint or lightheaded
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When do Solifenacin possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Dry mouth
Constipation
Blurry vision
Risk of severe swelling
Risk of abnormal heart rhythm
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Solifenacin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Constipation

stomach pain

Less common

Bladder pain

bloody or cloudy urine

blurred vision

chills

decrease in the frequency of urination

decrease in urine volume

difficult, burning, or painful urination

dizziness

dry eyes

fever

frequent urge to urinate

headache

lower back or side pain

nervousness

pounding in the ears

slow or fast heartbeat

swelling of the lower legs

unusual tiredness or weakness

Incidence not known

Bloating or swelling of the face, arms, hands, lower legs, or feet

body aches or pain

chest pain or discomfort

confusion

cough

decreased or increased sweating

diarrhea

discouragement

dry skin

fainting

feeling sad or empty

general feeling of discomfort or illness

hives or welts, itching, skin rash

hoarseness

irregular heartbeat recurrent

irritability

joint pain

lack of appetite

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of interest or pleasure

muscle aches and pains

redness of the skin

runny or stuffy nose

seeing, hearing, or feeling things that are not there

shivering

sore throat

tender, swollen glands in the neck

tingling of the hands or feet

trouble concentrating

trouble with sleeping

trouble with swallowing

unusual weight gain or loss

voice changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Dry mouth

Less common

Acid or sour stomach

belching

heartburn

indigestion

nausea

stomach discomfort or upset

vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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