Typical dosage for Dacarbazine
Your oncologist will calculate your dose based on your body surface area (BSA; in units of m2), which takes into account your height and weight.
The dose will also vary depending on what type of cancer you have and which other medications you’re taking with Dacarbazine.
- Hodgkin’s lymphoma: The most common dose is 375 mg/m2 injected into the vein (IV) every 2 weeks.
- Metastatic melanoma: The recommended dose is 250 mg/m2 given IV once per day for 5 days (can be repeated every 3 weeks). Another dosing option is 2 mg/kg to 4.5 mg/kg of body weight per day given IV for 10 days (can be repeated every 4 weeks).
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Reviewed by:
Allison Baxley, PharmD, BCOPAllison is a Board Certified Oncology Pharmacist with more than 12 years of clinical experience in oncology. After completing her residency, she accepted a position at the OU Health Stephenson Cancer Center and she has remained there ever since.

Reviewed by:
Cydnee Ng, PharmDCydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.