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Contrave: How It Works, How to Take It, and Side Effects
Contrave reduces appetite and cravings to support weight loss.
Written by Lauren Smith, MA | Reviewed by Stacia Woodcock, PharmD
Published on April 10, 2025Contrave is a combination of two medications: naltrexone and bupropion. Together, these medications may help manage food cravings and appetite, which may help support weight loss.
Additional Medical Contributors
- Joshua Murdock, PharmD, BCBBSJoshua Murdock, PharmD is a pharmacy editor for GoodRx. He earned his Doctor of Pharmacy degree from Butler University in Indianapolis, Indiana and is licensed in Colorado and Rhode Island.
References
Billes, S.K., et al. (2014). Naltrexone/bupropion for obesity: An investigational combination pharmacotherapy for weight loss. Pharmacological Research.
Nalpropion Pharmaceuticals LLC. (2023). CONTRAVE EXTENDED-RELEASE- naltrexone hydrochloride and bupropion hydrochloride tablet, extended release [package insert]. DailyMed.
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