Nubeqa vs. Xtandi for Prostate Cancer: Important Differences and Potential Risks.

Nubeqa

(darolutamide)

Xtandi

(enzalutamide)

Summary for Nubeqa

Prescription only

Nubeqa (darolutamide) is a prescription medication used to treat certain types of prostate cancer in adults. You usually take it along with other hormone treatments, with chemotherapy, or after surgery to remove the testicles. As an androgen receptor inhibitor, it blocks testosterone from helping prostate cancer grow. You take the tablet by mouth twice a day with food. Common side effects include low white blood cell count, tiredness, and rash.

Indications for Nubeqa

Non-metastatic prostate cancer that's castration-resistant
Metastatic prostate cancer that's hormone-sensitive, taken alone
Metastatic prostate cancer that's hormone-sensitive, used together with a chemotherapy medication called docetaxel

Pros and Cons for Nubeqa

Pros

Available as a pill you take by mouth
Recommended option for certain types of prostate cancer
Might cause fewer brain-related side effects than similar medications

Cons

Need to take it twice a day
Must take your dose with food
Can interact with many medications and products

Common Side Effects for Nubeqa

Non-metastatic prostate cancer:

Rise in liver enzymes (up to 23%)
Lower white blood cell count (20%)
Tiredness (16%)

Metastatic prostate cancer (when taken alone):

Rise in liver enzymes (up to 32%)
Lower white blood cell count (16%)

Metastatic prostate cancer (when taken with docetaxel):

Lower red blood cell count (72%)
Higher blood sugar levels (57%)
Lower white blood cell count (up to 52%)
Rise in liver enzymes (up to 40%)
Low calcium levels (31%)
Constipation (23%)
Rash (20%)

Warnings for Nubeqa

Heart problems
Seizure
Harm to unborn baby

Summary for Xtandi

Prescription only

Xtandi (enzalutamide) is a prescription cancer medication used to treat certain types of prostate cancer in adults. It works by blocking testosterone, a hormone that many prostate cancers need to grow. You usually take a tablet or capsule once a day by mouth, often along with other hormone treatments or after surgery to remove the testicles. Common side effects include weakness or fatigue, back pain, and hot flashes.

Indications for Xtandi

Prostate cancer that's castration-resistant
Metastatic prostate cancer that's hormone-sensitive
Non-metastatic prostate cancer that's hormone-sensitive, with a high risk of spreading

Pros and Cons for Xtandi

Pros

Pill that’s taken by mouth once a day
Can take with or without food
Recommended option for certain types of prostate cancer

Cons

Interacts with many medications
Can raise your risk for seizures and fractures
Requires regular blood tests and monitoring

Common Side Effects for Xtandi

Muscle and joint pain
Feeling more tired than usual
Hot flashes
Constipation
Reduced appetite
Diarrhea
High blood pressure
Bleeding problems
Falls
Bone fractures
Headache

Warnings for Xtandi

Seizures
Brain problem
Allergic reaction
Heart problems
Falls and fractures
Possible harm to unborn baby
Choking and trouble swallowing

Prices with our coupons for Nubeqa vs. Xtandi

Nubeqa120 tablets / 300mg

$16,136.15-

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Xtandi60 tablets / 80mg

$16,405.45-

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Nubeqa vs. Xtandi

Nubeqa

Xtandi

Summary for Nubeqa

Indications for Nubeqa

Pros and Cons for Nubeqa

Pros

Cons

Common Side Effects for Nubeqa

Warnings for Nubeqa

Summary for Xtandi

Indications for Xtandi

Pros and Cons for Xtandi

Pros

Cons

Common Side Effects for Xtandi

Warnings for Xtandi

Prices with our coupons for Nubeqa vs. Xtandi

Compare other Prostate Cancer drugs

Browse medications by letter

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Nubeqa

Xtandi

Summary for Nubeqa

Indications for Nubeqa

Pros and Cons for Nubeqa

Pros

Cons

Common Side Effects for Nubeqa

Warnings for Nubeqa

Summary for Xtandi

Indications for Xtandi

Pros and Cons for Xtandi

Pros

Cons

Common Side Effects for Xtandi

Warnings for Xtandi