Compare Nubeqa vs. Xtandi
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Nubeqa (darolutamide)Xtandi (enzalutamide)
- Nubeqa (darolutamide)Xtandi (enzalutamide)
Summary of Nubeqa vs. Xtandi
Summary for Androgen receptor inhibitorPrescription onlyNubeqa (darolutamide) is a prescription medication used to treat certain types of prostate cancer in adults. You usually take it along with other hormone treatments, with chemotherapy, or after surgery to remove the testicles. As an androgen receptor inhibitor, it blocks testosterone from helping prostate cancer grow. You take the tablet by mouth twice a day with food. Common side effects include low white blood cell count, tiredness, and rash.
Summary for AnticancerPrescription onlyXtandi (enzalutamide) is an oral medication used to treat certain types of prostate cancer. It’s a form of hormonal therapy called an antiandrogen that works to block testosterone in your body. Xtandi (enzalutamide) is one of the recommended options for prostate cancer and is taken once a day. But it should be used in combination with another hormonal medication that targets gonadotropin-releasing hormone (GnRH), unless you’ve had surgery to remove both testicles (bilateral orchiectomy).
Indications of Nubeqa vs. Xtandi
Indications for•Metastatic prostate cancer that's hormone-sensitive, taken alone•Metastatic prostate cancer that's hormone-sensitive, used together with a chemotherapy medication called docetaxelIndications for•Advanced or metastatic prostate cancerPros and Cons of Nubeqa vs. Xtandi
Pros and Const for Androgen receptor inhibitorPros•Available as a pill you take by mouth•Recommended option for certain types of prostate cancer•Might cause fewer brain-related side effects than similar medicationsCons•Need to take it twice a day•Must take your dose with food•Can interact with many medications and productsPros and Const for AnticancerPros•Oral pill, taken once daily•Recommended option for certain types of prostate cancer•Can treat prostate cancer that is no longer responding to other hormonal therapiesCons•Available as brand only, so can be expensive•Can interact with other medications•Can raise your risk for seizuresCommon Side Effects of Nubeqa vs. Xtandi
Common Side Effects forNon-metastatic prostate cancer:
Metastatic prostate cancer (when taken alone):
•Rise in liver enzymes (up to 32%)•Lower white blood cell count (16%)Metastatic prostate cancer (when taken with docetaxel):
•Lower red blood cell count (72%)•Higher blood sugar levels (57%)•Lower white blood cell count (up to 52%)•Rise in liver enzymes (up to 40%)•Low calcium levels (31%)•Constipation (23%)•Rash (20%)Common Side Effects for•Weakness or fatigue (up to 51%)•Back pain (up to 29%)•Hot flashes (up to 27%)•Constipation (up to 23%)•Diarrhea (up to 22%)•Joint pain (up to 21%)•Feeling less hungry (up to 19%)•High blood pressure (up to 14%)Warnings of Nubeqa vs. Xtandi
Common Side Effects for•Heart problems•Seizure•Harm to unborn babyCommon Side Effects for•Seizures•Swelling and narrowing of the blood vessels in your brain•Heart problems•Falls and fractures•Possible harm to unborn babyPrices with our coupons for Nubeqa vs. Xtandi
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