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Compare Nubeqa vs. Xtandi

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Nubeqa (darolutamide)
    Xtandi (enzalutamide)
  • Nubeqa (darolutamide)
    Xtandi (enzalutamide)

  • Summary of Nubeqa vs. Xtandi

    Summary for Androgen receptor inhibitor
    Prescription only

    Nubeqa (darolutamide) is a prescription medication used to treat certain types of prostate cancer in adults. You usually take it along with other hormone treatments, with chemotherapy, or after surgery to remove the testicles. As an androgen receptor inhibitor, it blocks testosterone from helping prostate cancer grow. You take the tablet by mouth twice a day with food. Common side effects include low white blood cell count, tiredness, and rash.

    Summary for Androgen receptor inhibitor
    Prescription only

    Xtandi (enzalutamide) is a prescription cancer medication used to treat certain types of prostate cancer in adults. It works by blocking testosterone, a hormone that many prostate cancers need to grow. You usually take a tablet or capsule once a day by mouth, often along with other hormone treatments or after surgery to remove the testicles. Common side effects include weakness or fatigue, back pain, and hot flashes.

  • Indications of Nubeqa vs. Xtandi

    Indications for
    •Non-metastatic prostate cancer that's castration-resistant
    •Metastatic prostate cancer that's hormone-sensitive, taken alone
    •Metastatic prostate cancer that's hormone-sensitive, used together with a chemotherapy medication called docetaxel
    Indications for
    •Prostate cancer that's castration-resistant
    •Metastatic prostate cancer that's hormone-sensitive
    •Non-metastatic prostate cancer that's hormone-sensitive, with a high risk of spreading

  • Pros and Cons of Nubeqa vs. Xtandi

    Pros and Const for Androgen receptor inhibitor
    Pros
    •Available as a pill you take by mouth
    •Recommended option for certain types of prostate cancer
    •Might cause fewer brain-related side effects than similar medications
    Cons
    •Need to take it twice a day
    •Must take your dose with food
    •Can interact with many medications and products
    Pros and Const for Androgen receptor inhibitor
    Pros
    •Pill that’s taken by mouth once a day
    •Can take with or without food
    •Recommended option for certain types of prostate cancer
    Cons
    •Interacts with many medications
    •Can raise your risk for seizures and fractures
    •Requires regular blood tests and monitoring

  • Common Side Effects of Nubeqa vs. Xtandi

    Common Side Effects for

    Non-metastatic prostate cancer:

    •Rise in liver enzymes (up to 23%)
    •Lower white blood cell count (20%)
    •Tiredness (16%)

    Metastatic prostate cancer (when taken alone):

    •Rise in liver enzymes (up to 32%)
    •Lower white blood cell count (16%)

    Metastatic prostate cancer (when taken with docetaxel):

    •Lower red blood cell count (72%)
    •Higher blood sugar levels (57%)
    •Lower white blood cell count (up to 52%)
    •Rise in liver enzymes (up to 40%)
    •Low calcium levels (31%)
    •Constipation (23%)
    •Rash (20%)
    Common Side Effects for
    •Muscle and joint pain
    •Feeling more tired than usual
    •Hot flashes
    •Constipation
    •Reduced appetite
    •Diarrhea
    •High blood pressure
    •Bleeding problems
    •Falls
    •Bone fractures
    •Headache

  • Warnings of Nubeqa vs. Xtandi

    Common Side Effects for
    •Heart problems
    •Seizure
    •Harm to unborn baby
    Common Side Effects for
    •Seizures
    •Brain problem
    •Allergic reaction
    •Heart problems
    •Falls and fractures
    •Possible harm to unborn baby
    •Choking and trouble swallowing

  • Prices with our coupons for Nubeqa vs. Xtandi

    Learn more about Nubeqa
    Learn more about Xtandi

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