Nextstellis
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Slynd
(drospirenone)
Get free couponsSummary for Nextstellis
Nextstellis is a combination birth control pill that's used to help prevent pregnancy. It contains two hormones: drospirenone and estetrol. Nextstellis is the first birth control pill that contains estetrol, a new type of estrogen approved in over 60 years that's also made from a plant source. Each blister card has 24 pink active pills and 4 white inactive pills. Each pill is taken by mouth once daily in the order noted in the instructions. The active pills are monophasic, meaning they contain the same amount of hormones throughout the entire pack. Side effects include irregular vaginal bleeding and mood changes.
Indications for Nextstellis
- To prevent pregnancy
Pros and Cons for Nextstellis
Pros
- First birth control pill containing estetrol (a different type of estrogen than ethinyl estradiol)
- Few people had breakthrough bleeding during studies
Cons
- Must take every day around the same time to work well
- No lower-cost generic available; brand name only
Common Side Effects for Nextstellis
- Mood changes or mood swings (11%)
- Irregular vaginal bleeding (10%)
- Breast symptoms, like changes in color or size, breast pain, or swelling (5%)
- Headache (5%)
Warnings for Nextstellis
- Cigarette smoking and risk for blood clots
- Blood clots and other complications
- High potassium levels in the blood
- High blood pressure
- Stop taking if you have a migraine
- Risk for breast and cervical cancer
- Liver or gallbladder problems
- High blood sugar
- High cholesterol levels
- Possible need for changes to thyroid hormone replacement therapy
- Irregular bleeding
- Depression
- Worsening of other health conditions
Summary for Slynd
Slynd (drospirenone) is a progestin-only contraceptive pill taken to prevent pregnancy. It's a non-estrogen option that might be more appropriate for people who smoke or have a history of blood clots. Slynd (drospirenone) is taken by mouth once daily. There are 24 active pills in each 28-day dosing cycle. Slynd (drospirenone) has a 24-hour missed pill window, which is more forgiving compared to other progestin-only birth control pills that have a 3-hour window. Some of the more common side effects of Slynd (drospirenone) include acne and changes in vaginal bleeding. Some people might also experience weight gain.
Indications for Slynd
- Prevention of pregnancy
Pros and Cons for Slynd
Pros
- Provides birth control option with no estrogen, which can be safer for some people (e.g., those at risk for clot or breast cancer)
- Less likely to cause irregular bleeding compared to other progestin-only pills that contain all active medication
- Longer missed pill window (24 hours) than other progestin-only birth control pills (3 hours)
- Safe to take while breastfeeding
Cons
- Must take every day to work well
- Need to use another form of non-hormonal birth control (a condom) for a week if you missed 2 or more white (active) pills
- No generics available
- Can cause acne as a side effect
Common Side Effects for Slynd
- Acne (4%)
- Breakthrough bleeding (3%)
- Headache (3%)
- Breast pain (2%)
Warnings for Slynd
- High blood potassium levels
- Very rare risk for blood clots, heart attacks, and strokes
- Liver problems
- High blood sugar
- Changes to menstrual bleeding (period) patterns
- Ectopic pregnancy
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