Nextstellis vs. Slynd for Birth Control: Important Differences and Potential Risks.

Nextstellis

Slynd

(drospirenone)

Summary for Nextstellis

Prescription only

Nextstellis is a combination birth control pill that's used to help prevent pregnancy. It contains two hormones: drospirenone and estetrol. Nextstellis is the first birth control pill that contains estetrol, a new type of estrogen approved in over 60 years that's also made from a plant source. Each blister card has 24 pink active pills and 4 white inactive pills. Each pill is taken by mouth once daily in the order noted in the instructions. The active pills are monophasic, meaning they contain the same amount of hormones throughout the entire pack. Side effects include irregular vaginal bleeding and mood changes.

Indications for Nextstellis

To prevent pregnancy

Pros and Cons for Nextstellis

Pros

First birth control pill containing estetrol (a different type of estrogen than ethinyl estradiol)
Few people had breakthrough bleeding during studies

Cons

Must take every day around the same time to work well
No lower-cost generic available; brand name only

Common Side Effects for Nextstellis

Mood changes or mood swings (11%)
Irregular vaginal bleeding (10%)
Breast symptoms, like changes in color or size, breast pain, or swelling (5%)
Headache (5%)

Warnings for Nextstellis

Cigarette smoking and risk for blood clots
Blood clots and other complications
High potassium levels in the blood
High blood pressure
Stop taking if you have a migraine
Risk for breast and cervical cancer
Liver or gallbladder problems
High blood sugar
High cholesterol levels
Possible need for changes to thyroid hormone replacement therapy
Irregular bleeding
Depression
Worsening of other health conditions

Summary for Slynd

Prescription only

Slynd (drospirenone) is a progestin-only contraceptive pill taken to prevent pregnancy. It's a non-estrogen option that might be more appropriate for people who smoke or have a history of blood clots. Slynd (drospirenone) is taken by mouth once daily. There are 24 active pills in each 28-day dosing cycle. Slynd (drospirenone) has a 24-hour missed pill window, which is more forgiving compared to other progestin-only birth control pills that have a 3-hour window. Some of the more common side effects of Slynd (drospirenone) include acne and changes in vaginal bleeding. Some people might also experience weight gain.

Indications for Slynd

Prevention of pregnancy

Pros and Cons for Slynd

Pros

Provides birth control option with no estrogen, which can be safer for some people (e.g., those at risk for clot or breast cancer)
Less likely to cause irregular bleeding compared to other progestin-only pills that contain all active medication
Longer missed pill window (24 hours) than other progestin-only birth control pills (3 hours)
Safe to take while breastfeeding

Cons

Must take every day to work well
Need to use another form of non-hormonal birth control (a condom) for a week if you missed 2 or more white (active) pills
No generics available
Can cause acne as a side effect

Common Side Effects for Slynd

Acne (4%)
Breakthrough bleeding (3%)
Headache (3%)
Breast pain (2%)

Warnings for Slynd

High blood potassium levels
Very rare risk for blood clots, heart attacks, and strokes
Liver problems
High blood sugar
Changes to menstrual bleeding (period) patterns
Ectopic pregnancy

Prices with our coupons for Nextstellis vs. Slynd

Nextstellis1 package / 28 tablets of 3mg/14.2mg

$65.00$264.48

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Slynd1 package / 28 tablets of 4mg

$200.01$232.91

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Nextstellis vs. Slynd

Nextstellis

Slynd

Summary for Nextstellis

Indications for Nextstellis

Pros and Cons for Nextstellis

Pros

Cons

Common Side Effects for Nextstellis

Warnings for Nextstellis

Summary for Slynd

Indications for Slynd

Pros and Cons for Slynd

Pros

Cons

Common Side Effects for Slynd

Warnings for Slynd

Prices with our coupons for Nextstellis vs. Slynd

Compare other Birth Control drugs

Browse medications by letter

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Nextstellis

Slynd

Summary for Nextstellis

Indications for Nextstellis

Pros and Cons for Nextstellis

Pros

Cons

Common Side Effects for Nextstellis

Warnings for Nextstellis

Summary for Slynd

Indications for Slynd

Pros and Cons for Slynd

Pros

Cons

Common Side Effects for Slynd

Warnings for Slynd