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Compare Apri vs. Sprintec

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Apri (desogestrel/ethinyl estradiol) and Sprintec (norgestimate/ethinyl estradiol) are both combined oral contraceptives (COCs) that contain estrogen and progestin to prevent pregnancy. Apri contains desogestrel as the progestin component, while Sprintec contains norgestimate. Both medications are monophasic, meaning all active tablets have the same hormone levels. Apri's active tablets contain 0.15 mg of desogestrel and 30 mcg of ethinyl estradiol, whereas Sprintec's active tablets contain 0.25 mg of norgestimate and 35 mcg of ethinyl estradiol. Both are taken daily for 21 days followed by 7 days of placebo tablets. Apri and Sprintec share similar side effects and risks, such as blood clots, high blood pressure, and mood changes. In addition, COCs are not recommended for females over 35 who smoke. Both are available as lower-cost generics and require a prescription.

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