Key takeaways
Midazolam (Seizalam, Versed) and Propofol (Diprivan) are both used for sedation, but they have some key differences. Midazolam, available under the brand name Seizalam, is a benzodiazepine that can be given as an injection, oral syrup, and nasal solution. It is used for sedation before medical procedures and for treating long-lasting seizures. Propofol, known by the brand name Diprivan, is a sedative used to put people to sleep during surgery or other medical procedures and is only available as an injection. Unlike Midazolam, Propofol is not a controlled medication. Midazolam can cause severe breathing problems and memory loss, while Propofol can lead to low blood pressure and a rare condition called propofol infusion syndrome (PRIS). Both medications require administration by a healthcare provider in a monitored setting.
