Compare Midazolam vs. Propofol

Midazolam (Seizalam, Versed) and Propofol (Diprivan) are both used for sedation, but they have some key differences. Midazolam is a benzodiazepine that can be given as an injection or oral syrup. It is used for sedation before medical procedures and for treating long-lasting seizures. Propofol is a sedative used to put people to sleep during surgery or other medical procedures and is only available as an injection. Unlike Midazolam, Propofol is not a controlled medication and works by binding to a specific protein in the brain called the GABA receptor. Midazolam can cause severe breathing problems and memory issues, while Propofol can lead to low blood pressure and a rare condition called propofol infusion syndrome (PRIS). Both medications require administration by a healthcare provider in a monitored setting.