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Lidoderm vs. Voltaren gel

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lidoderm (lidocaine) and Voltaren gel (diclofenac) are both used to relieve pain, but they work in different ways and are used for different types of pain. Lidoderm is a local anesthetic that numbs the nerves to reduce pain, and it is available in both prescription and over-the-counter forms. It is mainly used for nerve pain, such as pain from shingles. On the other hand, Voltaren gel is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and swelling by blocking certain chemicals in the body. It is used to treat pain from osteoarthritis in joints like the knees, hands, and wrists, and is available both by prescription and over-the-counter. While Lidoderm can cause mild skin irritation, Voltaren gel can lead to more serious side effects like heart attack, stroke, and stomach bleeding, especially if used in high doses or for a long time. Additionally, Voltaren gel should not be used on the back or hips, whereas Lidoderm patches can be cut to fit smaller areas of pain.

Lidocaine 5% patch

(Lidoderm)

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Diclofenac sodium topical gel

(Voltaren gel)

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Summary for Lidoderm

Prescription only

Lidocaine 5% patch (Lidoderm) is a prescription medication used to relieve nerve pain caused by a shingles infection, also called postherpetic neuralgia (PHN). It's a local anesthetic that works by numbing your nerves to help reduce pain. You apply the patch directly to the painful area of your skin once a day, and it can be worn for up to 12 hours in a 24-hour period. Common side effects include temporary skin irritation, redness, and a mild burning sensation where the patch is applied.

Indications for Lidoderm

Pros and Cons for Lidoderm

Pros

  • Works directly on the skin
  • Generally well-tolerated with few side effects
  • Can cut patches to fit the area of pain

Cons

  • Commonly causes skin irritation
  • Must avoid contact with water wearing the patch
  • Might interact with many medications

Common Side Effects for Lidoderm

  • Blisters
  • Bruising
  • Burning sensation
  • Changes in skin color
  • Rash or redness
  • Swelling
  • Peeling or flaking skin
  • Itching
  • Small bumps or spots
  • Tiny red or purple dots under the skin
  • Tingling or numbness in the area

Warnings for Lidoderm

  • Blood problem (methemoglobinemia)
  • Absorbing too much medication
  • Accidental poisoning in children or pets

Summary for Voltaren gel

Prescription or over-the-counter

Topical diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It helps temporarily relieve pain from osteoarthritis in adults. This medication comes as a %1 gel as generic and brand name (commonly Voltaren gel). It's available over the counter. There are also topical solutions of various strengths by prescription only. You apply the medication to the skin of the affected joints, up to 2 or 4 times daily. The exact dosage and number of times per day depends on which form you use. Side effects include dry skin, skin irritation, and itching. More serious risks include high blood pressure and stomach issues, but the potential is low.

Indications for Voltaren gel

  • Pain from osteoarthritis of the knee - topical solutions and 1% gel
  • Pain from osteoarthritis of small joints, such as hands, wrists, elbows, or feet - 1% gel only

Pros and Cons for Voltaren gel

Pros

  • Can help relieve specific areas of osteoarthritis pain
  • 1% gel available over the counter without a prescription
  • Less serious side effects than taking diclofenac pills by mouth

Cons

  • Doesn't provide relief right away
  • Can be inconvenient to use because you need to wait for the medication to dry before putting on clothing
  • Not for minor sprains, bruises, or other joints (like the back or hip)

Common Side Effects for Voltaren gel

1% gel:

  • Skin irritation (e.g., redness, rash, itchiness; 4%)

1.5% solution:

  • Dry skin (32%)
  • Skin irritation (9%)
  • Indigestion (8%)
  • Stomach pain (6%)

Warnings for Voltaren gel

  • Risk of heart attack and stroke
  • Risk of stomach ulcers and stomach bleeding
  • Liver damage
  • High blood pressure
  • Swelling and risk of heart failure
  • Kidney damage
  • High potassium levels
  • Worsening asthma in certain people
  • Severe allergic reaction or skin reaction
  • Risk of general bleeding and anemia
  • Higher risk of serious side effects when used together with oral NSAIDs
  • Harm to an unborn baby

Prices with our coupons for Lidoderm vs. Voltaren gel

Price Card Drug Icon
Lidocaine30 patches / 5%
$60.46$288.87
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Price Card Drug Icon
Diclofenac Sodium1 tube / 100g of 1%
$12.25$26.79
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