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Compare Avapro vs. Aceon

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Irbesartan (Avapro) and perindopril (Aceon) are both medications used to treat high blood pressure, but they belong to different drug classes. Irbesartan is an angiotensin II receptor blocker (ARB), while perindopril is an angiotensin-converting enzyme (ACE) inhibitor. Irbesartan is also used to treat diabetic kidney disease, whereas perindopril is used to lower the risk of death or heart attack in people with coronary artery disease (CAD). One key difference is that irbesartan is less likely to cause a dry cough compared to perindopril, which commonly causes this side effect. Both medications are available as lower-cost generics and are typically taken once a day. However, both medications have the potential to raise potassium levels and requires regular blood work to monitor kidney health. Neither medication is safe to use during pregnancy.

  • Irbesartan (Avapro)
    Perindopril
  • Irbesartan (Avapro)
    Perindopril

  • Summary of Avapro vs. Aceon

    Summary for ARB
    Prescription only

    Irbesartan (Avapro) is a medication that's used to treat high blood pressure; it's also used to treat diabetic kidney disease. It's a part of a drug class called angiotensin II receptor blockers (ARB). The dosage for irbesartan (Avapro) can differ if you've kidney problems or are taking diuretics ("water pills"). Common side effects include dizziness and tiredness. Irbesartan (Avapro) is available in both brand name (Avapro) and generic tablet.

    Summary for ACE inhibitor
    Prescription only

    Perindopril is a prescription medication that's used to treat high blood pressure. It's also used to lower the risk of death or heart attack in certain people with coronary artery disease (CAD). The dosage for perindopril can differ if you're older, have kidney problems, or are taking diuretics ("water pills"). Common side effects include dry cough, dizziness, and back pain. Although the brand name for this medication, Aceon, is discontinued, perindopril is available as a lower-cost, generic tablet.

  • Indications of Avapro vs. Aceon

    Indications for
    •Treatment of high blood pressure
    •Slow the worsening of kidney disease from diabetes
    Indications for
    •Treatment of high blood pressure
    •Treatment of stable coronary artery disease (CAD) in certain people to lower the risk of death or heart attack

  • Pros and Cons of Avapro vs. Aceon

    Pros and Const for ARB
    Pros
    •Available as a lower-cost generic medication
    •Typically taken once a day
    •Less likely to cause dry cough compared to ACE Inhibitors
    Cons
    •Not safe for use while pregnant
    •High risk of raising potassium levels
    •Requires regular blood work to make sure your kidneys are healthy
    Pros and Const for ACE inhibitor
    Pros
    •Available as a lower-cost generic medication
    •Typically taken once a day
    •Lowers the risk of heart attack or death due to heart problems in people with CAD
    Cons
    •Can’t take while pregnant
    •More likely to cause dry cough compared to angiotensin II receptor blockers (ARBs)
    •Might cause severe swelling of the face, tongue, throat (angioedema)

  • Common Side Effects of Avapro vs. Aceon

    Common Side Effects for
    •Dizziness (up to 10%)
    •Low blood pressure when going from sitting to standing position (5%)
    •Feeling tired (4%)
    •Diarrhea (3%)
    •Heartburn (2%)

    Please note: People who took irbesartan (Avapro) for high blood pressure were more likely to experience tiredness, diarrhea, and heartburn. People who took this medication for diabetic kidney disease were more likely to experience dizziness.

    Common Side Effects for
    •Cough (12%)
    •Dizziness (8%)
    •Back pain (6%)

  • Warnings of Avapro vs. Aceon

    Common Side Effects for
    •Harm to unborn baby
    •Low blood pressure
    •Worsening kidney problems
    •High levels of potassium
    Common Side Effects for
    •Harm to unborn baby
    •Angioedema (swelling)
    •Low blood pressure
    •Worsening kidney problems
    •Low blood cell count
    •High levels of potassium
    •Dry cough
    •Liver problems

  • Prices with our coupons for Avapro vs. Aceon

    Learn more about Irbesartan
    Learn more about Perindopril

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