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Arthrotec vs. Mobic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Arthrotec (diclofenac/misoprostol) and meloxicam (Mobic) are both prescription non-steroidal anti-inflammatory drugs (NSAIDs) used to treat arthritis pain, but they have some key differences. Arthrotec is a combination of diclofenac, which reduces inflammation and pain, and misoprostol, which protects the stomach from ulcers. Meloxicam works by blocking two proteins that can cause pain and swelling, and has less effects on the stomach compared to other NSAIDs. Arthrotec needs to be taken multiple times a day, while meloxicam is usually taken once daily. Both medications aren't safe for use in pregnant people. Additionally, meloxicam is available in various forms, including tablets, capsules, liquid, and injection, while Arthrotec is only available in tablet form. Both medications can cause serious side effects like heart attack, stroke, and stomach bleeding.

Arthrotec

(diclofenac / misoprostol)

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Meloxicam

 

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Summary for Arthrotec

Prescription only

Arthrotec (diclofenac / misoprostol) is a combination medication used to treat osteoarthritis (OA) and rheumatoid arthritis (RA) in non-pregnant adults. The diclofenac in Arthrotec is a non-steroidal anti-inflammatory drug (NSAID) that helps with pain and swelling, while the misoprostol is a prostaglandin E1 analog that lowers the risk of stomach and intestinal ulcers from diclofenac. Arthrotec (diclofenac / misoprostol) is taken by mouth, typically two to four times per day. Common side effects of this medication include stomach cramps (pain) and diarrhea. Avoid drinking alcohol with Arthrotec (diclofenac / misoprostol) because doing so can raise the risk of stomach bleeding.

Indications for Arthrotec

Pros and Cons for Arthrotec

Pros

  • Diclofenac works well to relieve symptoms of pain and swelling and misoprostol works well to lower the risk of stomach and intestinal ulcers and bleeding
  • Conveniently combines two medication in one pill
  • Available as a lower-cost generic

Cons

  • Needs to be taken multiple times a day
  • Not safe to take at any time of pregnancy
  • Might not be the best option if you're 65 years or older or if you have kidney, heart, liver, or bleeding problems

Common Side Effects for Arthrotec

  • Stomach pain (21%)
  • Diarrhea (19%)
  • Upset stomach or indigestion (14%)
  • Nausea (11%)
  • Gas (9%)

Warnings for Arthrotec

  • Harm to mother and unborn baby
  • Stomach bleeding
  • Heart attack and stroke
  • High blood pressure and heart failure
  • Kidney damage
  • Liver problems
  • Severe allergic reactions and skin reactions
  • Risk for bleeding

Summary for Mobic

Prescription only

Meloxicam is a prescription non-steroidal anti-inflammatory drug (NSAID). It's used for different types of arthritis pain. It comes as capsules, tablets and a liquid. All forms are for adults, but some are also for children of certain age and weight. Meloxicam is taken by mouth once a day. The dosage depends on your arthritis type, the form of meloxicam you're using, and age and weight for children. Common side effects include diarrhea, joint pain, and stomach upset. Like all NSAIDs, it can raise the risk of stomach bleeds. Meloxicam is a generic medication; its brand name Mobic is no longer available.

Indications for Mobic

Pros and Cons for Mobic

Pros

Cons

  • Available by prescription only
  • Might not be the best option for older adults or people with kidney, heart, liver, or bleeding problems
  • Can't switch easily between capsules, tablets, and liquid (can't be substituted for one another)

Common Side Effects for Mobic

  • Headache
  • Diarrhea
  • Indigestion
  • Nausea
  • Stomach pain
  • Joint pain
  • Flu-like symptoms

Warnings for Mobic

  • Risk of stomach ulcers and stomach bleeding
  • Risk of heart attack and stroke
  • High blood pressure
  • Swelling and risk of heart failure
  • Liver problems
  • Kidney damage
  • High potassium levels
  • Risk of general bleeding and anemia
  • Severe allergic reactions and skin reactions
  • Worsening asthma in certain people
  • Harm to an unborn baby

Prices with our coupons for Arthrotec vs. Mobic

Price Card Drug Icon
Diclofenac Sodium/Misoprostol60 tablets / 75mg/200mcg
$54.72$204.70
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Price Card Drug Icon
Meloxicam30 tablets / 15mg
$14.24$14.35
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